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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased susceptibility to myocardial ischemic injury
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Accession:MP:0031217 term browser browse the term
Definition:more severe response, such as increased incidence and/or size of necrotic tissue, to lack of adequate blood flow resulting from trauma or disease, to support the normal functioning of the myocardium compared to controls
Synonyms:exact_synonym: decreased resistance to myocardial ischaemic injury;   decreased resistance to myocardial ischemic injury;   increased susceptibility to myocardial ischaemic injury;   reduced resistance to myocardial ischaemic injury;   reduced resistance to myocardial ischemic injury



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increased myocardial infarct size term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ubd ubiquitin D IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221 NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639
JBrowse link
G Ubdem1 ubiquitin D; CRISPR/Cas9 induced mutant1 IMP associated with induced myocardial infarction RGD PMID:29438664 RGD:126925221

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5415
    homeostasis/metabolism phenotype 1421
      abnormal response to injury 39
        increased susceptibility to injury 12
          increased susceptibility to myocardial ischemic injury 3
            increased myocardial infarct size 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 5415
    cardiovascular system phenotype 1371
      abnormal cardiovascular system physiology 1148
        abnormal response to cardiac infarction 4
          abnormal response to myocardial ischemic injury 4
            increased susceptibility to myocardial ischemic injury 3
              increased myocardial infarct size 3
paths to the root