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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal glutamine level
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Accession:MP:0030705 term browser browse the term
Definition:anomaly in the amount of glutamine, a non-essential alpha-amino acid synthesized from glutamate and ammonia that may become conditionally essential in hypercatabolic states; glutamine plays several important roles, including protein and glutathione synthesis, energy production, acid-base balance, maintenance of optimal antioxidant status, intestinal integrity, immune function, gluconeogenesis, nitrogen transport, and neurotransmitter, nucleotide and nucleic acid synthesis



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Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S SD-Tg(SOD1*G93A)39 IMP CSF, compared to control littermates RGD PMID:11717358 RGD:2290184

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  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal amino acid level 77
          abnormal glutamine level 1
            abnormal circulating glutamine level + 0
            decreased glutamine level + 0
            increased glutamine level + 1
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