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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal serine level
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Accession:MP:0030690 term browser browse the term
Definition:anomaly in the amount of serine, 2-amino-3-hydroxypropanoic acid, a non-essential alpha-amino acid that is alanine substituted at position 3 by a hydroxy group; serine participates in the biosynthesis of purines and pyrimidines, is the precursor to glycine and cysteine and to numerous metabolites including sphingolipids and folate, and is often a hydrogen donor in enzymes, such as trypsin and chymotrypsin, playing a key role in their function as catalysts


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  mammalian phenotype 5417
    homeostasis/metabolism phenotype 1423
      abnormal homeostasis 1324
        abnormal amino acid level 77
          abnormal serine level 0
            abnormal circulating serine level + 0
            decreased serine level + 0
            increased serine level + 0
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