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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal manganese homeostasis
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Accession:MP:0030592 term browser browse the term
Definition:anomaly in the processes involved in the maintenance of an internal steady state of manganese ions within an organism or cell; manganese ions function as cofactors for a large variety of enzymes with many functions; while the element is a required trace mineral for all known living organisms, it also acts as a neurotoxin in larger amounts
Synonyms:exact_synonym: abnormal manganese ion homeostasis


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abnormal manganese level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc30a10 solute carrier family 30, member 10 IAGP MGI PMID:28461334 NCBI chr 1:185,187,045...185,200,959
Ensembl chr 1:185,187,045...185,200,959 		JBrowse link
decreased liver manganese level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sephs1 selenophosphate synthetase 1 IAGP MGI PMID:27208177 NCBI chr 2:4,886,375...4,915,368
Ensembl chr 2:4,886,375...4,915,368 		JBrowse link
G Speer6-ps1 spermatogenesis associated glutamate (E)-rich protein 6, pseudogene 1 IAGP MGI PMID:27208177 NCBI chr13:3,199,475...3,239,678
Ensembl chr13:3,236,206...3,239,317
Ensembl chr13:3,236,206...3,239,317 		JBrowse link
increased brain manganese level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc30a10 solute carrier family 30, member 10 IAGP MGI PMID:28461334 NCBI chr 1:185,187,045...185,200,959
Ensembl chr 1:185,187,045...185,200,959 		JBrowse link
increased circulating manganese level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc30a10 solute carrier family 30, member 10 IAGP MGI PMID:28461334 NCBI chr 1:185,187,045...185,200,959
Ensembl chr 1:185,187,045...185,200,959 		JBrowse link
increased liver manganese level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc30a10 solute carrier family 30, member 10 IAGP MGI PMID:28461334 NCBI chr 1:185,187,045...185,200,959
Ensembl chr 1:185,187,045...185,200,959 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 16478
    homeostasis/metabolism phenotype 7551
      abnormal homeostasis 6716
        abnormal mineral homeostasis 1045
          abnormal manganese homeostasis 3
            abnormal manganese level + 3
paths to the root