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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased microglial cell activation
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Accession:MP:0020448 term browser browse the term
Definition:increase in the change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, during the maturation to the fully active phagocytic form



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increased microglial cell activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atm ATM serine/threonine kinase IMP DNA:deletion:exon: RGD PMID:28007901 RGD:12879399 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atmem1Kyo ATM serine/threonine kinase; ZFN induced mutant 1, Kyo IMP RGD PMID:28007901 RGD:12879399

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5400
    nervous system phenotype 365
      abnormal nervous system physiology 206
        abnormal glial cell physiology 3
          abnormal microglial cell physiology 3
            abnormal microglial cell activation 3
              increased microglial cell activation 2
Path 2
Term Annotations click to browse term
  mammalian phenotype 5400
    hematopoietic system phenotype 247
      abnormal hematopoietic system physiology 61
        abnormal blood cell physiology 59
          abnormal leukocyte physiology 56
            abnormal macrophage physiology 5
              abnormal microglial cell physiology 3
                abnormal microglial cell activation 3
                  increased microglial cell activation 2
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