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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased microglial cell activation
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Accession:MP:0020448 term browser browse the term
Definition:increase in the change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, during the maturation to the fully active phagocytic form


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increased microglial cell activation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 IAGP MGI PMID:23500093 NCBI chr17:93,506,448...93,513,967
Ensembl chr17:93,506,445...93,513,965 		JBrowse link
G Bcap31 B cell receptor associated protein 31 IAGP MGI PMID:31883536 NCBI chr  X:72,729,784...72,761,464
Ensembl chr  X:72,729,784...72,759,781 		JBrowse link
G C3 complement component 3 IAGP MGI PMID:18562603 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IAGP MGI PMID:23637822 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin IAGP MGI PMID:32601357 NCBI chr 7:126,170,571...126,184,991
Ensembl chr 7:126,170,379...126,184,989 		JBrowse link
G Cox10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 10 IAGP MGI PMID:27038906 NCBI chr11:63,853,453...63,970,298
Ensembl chr11:63,853,453...63,970,294 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IAGP MGI PMID:23637822 NCBI chr 9:119,877,749...119,897,362
Ensembl chr 9:119,877,749...119,898,945 		JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 IAGP MGI PMID:35230417 NCBI chr 8:45,758,838...45,786,200
Ensembl chr 8:45,757,981...45,786,253 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:31883536 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 IAGP MGI PMID:31416892 NCBI chr19:37,184,939...37,201,856
Ensembl chr19:37,184,942...37,199,550 		JBrowse link
G Matr3 matrin 3 IAGP MGI PMID:33082323 NCBI chr18:35,686,462...35,724,526
Ensembl chr18:35,695,191...35,726,888 		JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 IAGP MGI PMID:22718760 NCBI chr 5:29,678,821...29,683,468
Ensembl chr 5:29,678,032...29,683,468 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 IAGP MGI PMID:19056848 PMID:22048958 PMID:26019327 NCBI chr18:12,322,751...12,369,851
Ensembl chr18:12,322,749...12,369,457 		JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 IAGP MGI PMID:31371497 NCBI chr 7:44,199,040...44,204,928
Ensembl chr 7:44,199,040...44,203,375 		JBrowse link
G Nudc nudC nuclear distribution protein IAGP MGI PMID:38441532 NCBI chr 4:133,259,853...133,273,338
Ensembl chr 4:133,259,853...133,273,307 		JBrowse link
G Pcare photoreceptor cilium actin regulator IAGP MGI PMID:25616964 NCBI chr17:72,050,919...72,059,904
Ensembl chr17:72,050,550...72,059,889 		JBrowse link
G Prcd photoreceptor disc component IAGP MGI PMID:31189593 NCBI chr11:116,544,603...116,559,224
Ensembl chr11:116,544,360...116,559,215 		JBrowse link
G Prph2 peripherin 2 IAGP MGI PMID:37914688 NCBI chr17:47,221,404...47,235,859
Ensembl chr17:47,221,385...47,235,859 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IAGP MGI PMID:14987753 NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
G Rsph9 radial spoke head 9 homolog (Chlamydomonas) IAGP MGI PMID:32709945 NCBI chr17:46,432,964...46,455,171
Ensembl chr17:46,432,961...46,455,142 		JBrowse link
G Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 IAGP MGI PMID:27038906 NCBI chr13:73,684,270...73,726,791
Ensembl chr13:73,684,866...73,726,791 		JBrowse link
G Ss18l1 SS18, nBAF chromatin remodeling complex subunit like 1 IAGP MGI PMID:30976389 NCBI chr 2:179,684,276...179,711,994
Ensembl chr 2:179,684,302...179,711,994 		JBrowse link
G Susd4 sushi domain containing 4 IAGP MGI PMID:32179479 NCBI chr 1:182,591,609...182,724,161
Ensembl chr 1:182,591,425...182,724,156 		JBrowse link
G Tardbp TAR DNA binding protein IAGP MGI PMID:22718760 NCBI chr 4:148,696,839...148,711,672
Ensembl chr 4:148,696,839...148,711,476 		JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 IAGP MGI PMID:35464428 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405 		JBrowse link
G Vps54 VPS54 GARP complex subunit IAGP MGI PMID:20643756 NCBI chr11:21,189,032...21,271,133
Ensembl chr11:21,189,281...21,271,136 		JBrowse link
G Zbtb20 zinc finger and BTB domain containing 20 IAGP MGI PMID:18562603 NCBI chr16:42,728,008...43,462,981
Ensembl chr16:42,696,244...43,462,965 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16965
    nervous system phenotype 4637
      abnormal nervous system physiology 2714
        abnormal glial cell physiology 151
          abnormal microglial cell physiology 77
            abnormal microglial cell activation 41
              increased microglial cell activation 27
Path 2
Term Annotations click to browse term
  mammalian phenotype 16965
    hematopoietic system phenotype 5540
      abnormal hematopoietic system physiology 2064
        abnormal blood cell physiology 1918
          abnormal leukocyte physiology 1784
            abnormal macrophage physiology 528
              abnormal microglial cell physiology 77
                abnormal microglial cell activation 41
                  increased microglial cell activation 27
paths to the root