MAMMALIAN PHENOTYPE - ANNOTATIONS
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term: impaired humoral immune response
Accession: MP:0020154
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Definition: impaired response of the immune system that mediates secreted antibodies produced in B cells
Synonyms: exact_synonym: impaired humoural immune response; low humoral immune response; low humoural immune response
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Atm
ataxia telangiectasia mutated
IEA
MGI
NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
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Card11
caspase recruitment domain family, member 11
IAGP
MGI
PMID:31784498
NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337
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Cd19
CD19 antigen
IAGP
MGI
PMID:25238757 PMID:33336366
NCBI chr 7:126,007,620...126,016,401
Ensembl chr 7:126,007,622...126,014,061
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Cd4
CD4 antigen
IEA
MGI
NCBI chr 6:124,841,656...124,865,210
Ensembl chr 6:124,841,655...124,865,184
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Cd40
CD40 antigen
IEA
MGI
NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
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Cd79a
CD79A antigen (immunoglobulin-associated alpha)
IEA
MGI
NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622
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Ciita
class II transactivator
IEA
MGI
NCBI chr16:10,297,877...10,348,928
Ensembl chr16:10,297,923...10,346,282
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Cr2
complement receptor 2
IEA
MGI
NCBI chr 1:194,819,120...194,859,096
Ensembl chr 1:194,819,119...194,859,024
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Ctps1
cytidine 5'-triphosphate synthase 1
IAGP
MGI
PMID:38438357
NCBI chr 4:120,397,065...120,427,473
Ensembl chr 4:120,397,065...120,427,473
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Ctss
cathepsin S
IEA
MGI
NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714
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Dclre1c
DNA cross-link repair 1C
IEA
MGI
NCBI chr 2:3,425,112...3,475,248
Ensembl chr 2:3,425,168...3,465,167
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Dock8
dedicator of cytokinesis 8
IEA
MGI
NCBI chr19:24,976,753...25,179,796
Ensembl chr19:24,976,898...25,179,796
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Ell2
elongation factor for RNA polymerase II 2
IAGP
MGI
PMID:25238757
NCBI chr13:75,855,603...75,920,480
Ensembl chr13:75,854,876...75,920,483
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Elmo1
engulfment and cell motility 1
IEA
MGI
NCBI chr13:20,274,677...20,792,523
Ensembl chr13:20,274,766...20,792,523
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Fasl
Fas ligand
IEA
MGI
NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
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Gt(ROSA)26Sor
gene trap ROSA 26, Philippe Soriano
IAGP
MGI
PMID:33336366 PMID:38438357
NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
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Itgb2
integrin beta 2
IEA
MGI
NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542
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Jak3
Janus kinase 3
IEA
MGI
NCBI chr 8:72,129,027...72,143,221
Ensembl chr 8:72,128,940...72,143,219
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Lig4
ligase IV, DNA, ATP-dependent
IEA
MGI
NCBI chr 8:10,020,020...10,027,680
Ensembl chr 8:10,019,049...10,027,686
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Lmbr1l
limb region 1 like
IAGP
MGI
PMID:31073040
NCBI chr15:98,801,798...98,815,944
Ensembl chr15:98,801,798...98,816,112
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Lyn
LYN proto-oncogene, Src family tyrosine kinase
IEA
MGI
NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122
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Malt1
MALT1 paracaspase
IEA
MGI
NCBI chr18:65,564,010...65,612,138
Ensembl chr18:65,564,009...65,612,138
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Mir148a
microRNA 148a
IAGP
MGI
PMID:33336366
NCBI chr 6:51,246,792...51,246,890
Ensembl chr 6:51,246,792...51,246,890
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Mzb1
marginal zone B and B1 cell-specific protein 1
IAGP
MGI
PMID:24888588
NCBI chr18:35,780,318...35,782,420
Ensembl chr18:35,780,320...35,782,420
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Nfkb1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
IEA
MGI
NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
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Pax5
paired box 5
IEA
MGI
NCBI chr 4:44,524,748...44,710,694
Ensembl chr 4:44,524,757...44,710,487
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Pik3ap1
phosphoinositide-3-kinase adaptor protein 1
IEA
MGI
NCBI chr19:41,260,980...41,373,541
Ensembl chr19:41,260,816...41,373,541
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Pnp
purine-nucleoside phosphorylase
IEA
MGI
NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869
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Prkcb
protein kinase C, beta
IEA
MGI
NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625
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Prkcq
protein kinase C, theta
IEA
MGI
NCBI chr 2:11,176,922...11,306,033
Ensembl chr 2:11,176,919...11,306,033
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Prkdc
protein kinase, DNA activated, catalytic polypeptide
IEA
MGI
NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099
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Rac2
Rac family small GTPase 2
IEA
MGI
NCBI chr15:78,443,369...78,456,983
Ensembl chr15:78,443,367...78,456,983
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Rel
reticuloendotheliosis oncogene
IEA
MGI
NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970
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Rorc
RAR-related orphan receptor gamma
IEA
MGI
NCBI chr 3:94,280,106...94,305,583
Ensembl chr 3:94,280,101...94,305,583
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Rragc
Ras-related GTP binding C
IAGP
MGI
PMID:34260908
NCBI chr 4:123,811,226...123,830,790
Ensembl chr 4:123,811,239...123,830,790
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Slfn2
schlafen 2
IEA
MGI
NCBI chr11:82,955,938...82,961,504
Ensembl chr11:82,955,938...82,961,504
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Stk4
serine/threonine kinase 4
IEA
MGI
NCBI chr 2:163,916,033...163,997,444
Ensembl chr 2:163,912,242...163,997,444
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Themis
thymocyte selection associated
IEA
MGI
NCBI chr10:28,544,356...28,759,816
Ensembl chr10:28,544,356...28,759,814
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Tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
IAGP
MGI
PMID:23676465
NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
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Tnfsf13b
tumor necrosis factor (ligand) superfamily, member 13b
IEA
MGI
NCBI chr 8:10,056,637...10,086,000
Ensembl chr 8:10,056,467...10,089,072
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Traf3
TNF receptor-associated factor 3
IEA
MGI
NCBI chr12:111,132,799...111,233,589
Ensembl chr12:111,132,804...111,233,587
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Trp53bp1
transformation related protein 53 binding protein 1
IEA
MGI
NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888
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Vav1
vav 1 oncogene
IEA
MGI
NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031
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Zap70
zeta-chain (TCR) associated protein kinase
IEA
MGI
NCBI chr 1:36,800,912...36,821,899
Ensembl chr 1:36,800,879...36,821,899
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Zeb1
zinc finger E-box binding homeobox 1
IEA
MGI
NCBI chr18:5,591,330...5,775,468
Ensembl chr18:5,591,860...5,775,467
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