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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased interferon level
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Accession:MP:0014435 term browser browse the term
Definition:more than the normal levels of of interferons
Synonyms:exact_synonym: elevated interferon level



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increased interferon level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trim29 tripartite motif-containing 29 IAGP MGI PMID:38664417 NCBI chr 9:43,222,012...43,247,422
Ensembl chr 9:43,222,145...43,247,412
JBrowse link
G Ube2s ubiquitin-conjugating enzyme E2S IAGP MGI PMID:32814047 NCBI chr 7:4,811,013...4,815,339
Ensembl chr 7:4,797,545...4,815,589
JBrowse link
increased circulating interferon-alpha level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adar adenosine deaminase, RNA-specific IAGP MGI PMID:19060901 NCBI chr 3:89,622,321...89,660,756
Ensembl chr 3:89,622,329...89,660,753
JBrowse link
G Ddx60 DExD/H box helicase 60 IAGP MGI PMID:25981042 NCBI chr 8:62,381,155...62,491,278
Ensembl chr 8:62,381,121...62,491,278
JBrowse link
G Fas Fas cell surface death receptor IAGP MGI PMID:16973389 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Gpr183 G protein-coupled receptor 183 IAGP MGI PMID:24386204 NCBI chr14:122,189,743...122,202,605
Ensembl chr14:122,189,963...122,202,607
JBrowse link
G Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated IAGP MGI PMID:29706547 NCBI chr 6:91,493,017...91,499,602
Ensembl chr 6:91,492,910...91,499,607
JBrowse link
G Phf6 PHD finger protein 6 IAGP MGI PMID:30755422 NCBI chr  X:52,001,091...52,045,838
Ensembl chr  X:52,001,143...52,045,820
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IEA MGI NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028
JBrowse link
G Prf1 perforin 1 (pore forming protein) IAGP MGI PMID:15069016 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
JBrowse link
G Rnf122 ring finger protein 122 IAGP MGI PMID:27506794 NCBI chr 8:31,601,855...31,623,346
Ensembl chr 8:31,601,848...31,621,510
JBrowse link
G Siglech sialic acid binding Ig-like lectin H IAGP MGI PMID:22177923 NCBI chr 7:55,417,916...55,429,196
Ensembl chr 7:55,417,926...55,428,673
JBrowse link
G Tlr9 toll-like receptor 9 IAGP MGI PMID:16973389 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082
JBrowse link
G Trim38 tripartite motif-containing 38 IAGP MGI PMID:26392463 NCBI chr13:23,962,483...23,975,721
Ensembl chr13:23,953,896...23,975,511
JBrowse link
G Ube2s ubiquitin-conjugating enzyme E2S IAGP MGI PMID:32814047 NCBI chr 7:4,811,013...4,815,339
Ensembl chr 7:4,797,545...4,815,589
JBrowse link
G Usp21 ubiquitin specific peptidase 21 IAGP MGI PMID:24493797 NCBI chr 1:171,109,523...171,115,534
Ensembl chr 1:171,109,519...171,115,564
JBrowse link
increased circulating interferon-beta level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccdc50 coiled-coil domain containing 50 IAGP MGI PMID:34453126 NCBI chr16:27,205,815...27,270,968
Ensembl chr16:27,207,619...27,270,968
JBrowse link
G Ddx46 DEAD box helicase 46 IAGP MGI PMID:28846086 NCBI chr13:55,782,790...55,829,080
Ensembl chr13:55,782,841...55,829,069
JBrowse link
G Fis1 fission, mitochondrial 1 IAGP MGI PMID:31526891 NCBI chr 5:136,982,129...136,995,088
Ensembl chr 5:136,982,129...136,995,088
JBrowse link
G Irf9 interferon regulatory factor 9 IEA MGI NCBI chr14:55,841,442...55,847,487
Ensembl chr14:55,841,028...55,847,487
JBrowse link
G Lsm3 LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated IAGP MGI PMID:29706547 NCBI chr 6:91,493,017...91,499,602
Ensembl chr 6:91,492,910...91,499,607
JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:36028484 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Marchf2 membrane associated ring-CH-type finger 2 IAGP MGI PMID:32935379 NCBI chr17:33,904,666...33,937,651
Ensembl chr17:33,904,666...33,937,644
JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 IAGP MGI PMID:26246171 NCBI chr19:37,184,939...37,201,856
Ensembl chr19:37,184,942...37,199,550
JBrowse link
G Mmp9 matrix metallopeptidase 9 IAGP MGI PMID:18332263 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Otud1 OTU domain containing 1 IAGP MGI PMID:32075857 NCBI chr 2:19,662,542...19,666,090
Ensembl chr 2:19,662,563...19,665,394
JBrowse link
G Prmt9 protein arginine methyltransferase 9 IAGP MGI PMID:36028484 NCBI chr 8:78,276,015...78,307,966
Ensembl chr 8:78,276,026...78,307,967
JBrowse link
G Rnf115 ring finger protein 115 IAGP MGI PMID:33139700 NCBI chr 3:96,634,869...96,698,471
Ensembl chr 3:96,634,980...96,698,954
JBrowse link
G Rnf122 ring finger protein 122 IAGP MGI PMID:27506794 NCBI chr 8:31,601,855...31,623,346
Ensembl chr 8:31,601,848...31,621,510
JBrowse link
G Snrnp40 small nuclear ribonucleoprotein 40 (U5) IAGP MGI PMID:31427773 NCBI chr 4:130,253,925...130,283,826
Ensembl chr 4:130,253,925...130,283,819
JBrowse link
G Tmem268 transmembrane protein 268 IAGP MGI PMID:38730209 NCBI chr 4:63,472,410...63,504,594
Ensembl chr 4:63,477,018...63,504,594
JBrowse link
G Trim38 tripartite motif-containing 38 IAGP MGI PMID:26392463 NCBI chr13:23,962,483...23,975,721
Ensembl chr13:23,953,896...23,975,511
JBrowse link
G Ube2s ubiquitin-conjugating enzyme E2S IAGP MGI PMID:32814047 NCBI chr 7:4,811,013...4,815,339
Ensembl chr 7:4,797,545...4,815,589
JBrowse link
G Usp21 ubiquitin specific peptidase 21 IAGP MGI PMID:24493797 NCBI chr 1:171,109,523...171,115,534
Ensembl chr 1:171,109,519...171,115,564
JBrowse link
G Usp49 ubiquitin specific peptidase 49 IAGP MGI PMID:30943264 NCBI chr17:47,941,615...47,997,664
Ensembl chr17:47,941,615...47,997,663
JBrowse link
G Wwp2 WW domain containing E3 ubiquitin protein ligase 2 IAGP MGI PMID:23479606 NCBI chr 8:108,162,966...108,285,922
Ensembl chr 8:108,162,997...108,285,227
JBrowse link
increased circulating interferon-gamma level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 IAGP MGI PMID:32485164 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Apoe apolipoprotein E IAGP MGI PMID:12765335 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Cav1 caveolin 1, caveolae protein IAGP MGI PMID:16982844 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IAGP MGI PMID:19641038 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Cd44 CD44 antigen IAGP MGI PMID:11342603 NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010
JBrowse link
G Cd79a CD79A antigen (immunoglobulin-associated alpha) IAGP MGI PMID:23955076 NCBI chr 7:24,596,922...24,601,283
Ensembl chr 7:24,596,806...24,601,622
JBrowse link
G Dhx58 DExH-box helicase 58 IAGP MGI PMID:17475874 NCBI chr11:100,585,710...100,595,165
Ensembl chr11:100,585,710...100,595,097
JBrowse link
G Dusp1 dual specificity phosphatase 1 IAGP MGI PMID:16424221 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Dusp22 dual specificity phosphatase 22 IAGP MGI PMID:24714587 NCBI chr13:30,844,042...30,895,215
Ensembl chr13:30,843,982...30,895,214
JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:16275384 PMID:34709178 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484
JBrowse link
G Gba1 glucosylceramidase beta 1 IAGP MGI PMID:20962279 NCBI chr 3:89,110,235...89,119,944
Ensembl chr 3:89,110,235...89,116,273
JBrowse link
G Gnai2 G protein subunit alpha i2 IAGP MGI PMID:17242370 NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566
JBrowse link
G Gpr183 G protein-coupled receptor 183 IAGP MGI PMID:24386204 NCBI chr14:122,189,743...122,202,605
Ensembl chr14:122,189,963...122,202,607
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:23955076 PMID:24376268 PMID:24498102 PMID:29263322 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,055,336
JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP MGI PMID:31964735 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977
JBrowse link
G Igtp interferon gamma induced GTPase IAGP MGI PMID:10639151 NCBI chr11:58,090,382...58,098,418
Ensembl chr11:58,090,382...58,098,417
JBrowse link
G Il10 interleukin 10 IAGP MGI PMID:12765335 PMID:19941312 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il10ra interleukin 10 receptor, alpha IAGP MGI PMID:19941312 NCBI chr 9:45,165,135...45,180,447
Ensembl chr 9:45,165,135...45,180,447
JBrowse link
G Il10rb interleukin 10 receptor, beta IAGP MGI PMID:18318596 NCBI chr16:91,203,166...91,222,718
Ensembl chr16:91,203,052...91,222,722
JBrowse link
G Il18bp interleukin 18 binding protein IAGP MGI PMID:28900426 PMID:29295842 NCBI chr 7:101,664,281...101,669,699
Ensembl chr 7:101,664,092...101,667,897
JBrowse link
G Il27ra interleukin 27 receptor, alpha IAGP MGI PMID:15004160 NCBI chr 8:84,756,915...84,769,250
Ensembl chr 8:84,756,923...84,769,218
JBrowse link
G Irf1 interferon regulatory factor 1 IAGP MGI PMID:9379011 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200
JBrowse link
G Irgm1 immunity-related GTPase family M member 1 IAGP MGI PMID:11457893 NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510
JBrowse link
G Klra8 killer cell lectin-like receptor, subfamily A, member 8 IAGP MGI PMID:15784573 NCBI chr 6:130,092,189...130,106,861
Ensembl chr 6:130,092,189...130,106,861
JBrowse link
G Lgals3bp lectin, galactoside-binding, soluble, 3 binding protein IAGP MGI PMID:10077627 NCBI chr11:118,283,573...118,292,787
Ensembl chr11:118,283,577...118,292,918
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IAGP MGI PMID:23940344 NCBI chr 4:3,676,865...3,791,613
Ensembl chr 4:3,678,115...3,813,122
JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:19941312 PMID:29263322 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226
JBrowse link
G Mavs mitochondrial antiviral signaling protein IAGP MGI PMID:20140199 NCBI chr 2:131,075,445...131,089,945
Ensembl chr 2:131,075,983...131,089,945
JBrowse link
G Mmp9 matrix metallopeptidase 9 IAGP MGI PMID:18332263 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mst1r macrophage stimulating 1 receptor (c-met-related tyrosine kinase) IAGP MGI PMID:17008558 NCBI chr 9:107,784,057...107,797,582
Ensembl chr 9:107,784,072...107,797,582
JBrowse link
G Mta2 metastasis-associated gene family, member 2 IAGP MGI PMID:18353770 NCBI chr19:8,919,239...8,929,659
Ensembl chr19:8,919,239...8,929,667
JBrowse link
G Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric IAGP MGI PMID:21502330 NCBI chr 7:141,342,695...141,372,964
Ensembl chr 7:141,342,709...141,372,968
JBrowse link
G Nfil3 nuclear factor, interleukin 3, regulated IAGP MGI PMID:24442434 NCBI chr13:53,121,245...53,136,914
Ensembl chr13:53,121,245...53,135,109
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IAGP MGI PMID:19139201 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IAGP MGI PMID:22396549 NCBI chr13:75,237,407...75,282,980
Ensembl chr13:75,237,945...75,282,980
JBrowse link
G Pgd phosphogluconate dehydrogenase IAGP MGI PMID:34709178 NCBI chr 4:149,234,448...149,251,162
Ensembl chr 4:149,234,448...149,251,228
JBrowse link
G Pilrb1 paired immunoglobin-like type 2 receptor beta 1 IAGP MGI PMID:20065029 NCBI chr 5:137,850,403...137,856,687
Ensembl chr 5:137,850,409...137,856,368
JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase, type II, gamma IAGP MGI PMID:27313209 NCBI chr10:127,032,936...127,047,508
Ensembl chr10:127,032,936...127,047,454
JBrowse link
G Pld3 phospholipase D family member 3 IAGP MGI PMID:30111894 NCBI chr 7:27,231,090...27,252,511
Ensembl chr 7:27,231,425...27,252,643
JBrowse link
G Pld4 phospholipase D family member 4 IAGP MGI PMID:30111894 NCBI chr12:112,727,089...112,735,420
Ensembl chr12:112,727,089...112,735,424
JBrowse link
G Prf1 perforin 1 (pore forming protein) IAGP MGI PMID:15069016 PMID:23160464 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IAGP MGI PMID:21435452 NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677
JBrowse link
G Pycard PYD and CARD domain containing IAGP MGI PMID:29263322 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
JBrowse link
G Rab27a RAB27A, member RAS oncogene family IAGP MGI PMID:23160464 NCBI chr 9:72,952,092...73,004,905
Ensembl chr 9:72,952,136...73,004,911
JBrowse link
G Ramp1 receptor (calcitonin) activity modifying protein 1 IAGP MGI PMID:17923674 NCBI chr 1:91,107,544...91,152,918
Ensembl chr 1:91,107,544...91,152,918
JBrowse link
G Rhbdd3 rhomboid domain containing 3 IAGP MGI PMID:23610400 NCBI chr11:5,048,282...5,056,100
Ensembl chr11:5,048,926...5,056,093
JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 IAGP MGI PMID:19923443 NCBI chr16:75,655,682...75,706,154
Ensembl chr16:75,655,681...75,819,169
JBrowse link
G Sirt3 sirtuin 3 IAGP MGI PMID:21856199 NCBI chr 7:140,443,576...140,462,222
Ensembl chr 7:140,443,579...140,462,222
JBrowse link
G Snrnp40 small nuclear ribonucleoprotein 40 (U5) IAGP MGI PMID:31427773 NCBI chr 4:130,253,925...130,283,826
Ensembl chr 4:130,253,925...130,283,819
JBrowse link
G Socs1 suppressor of cytokine signaling 1 IAGP MGI PMID:12705851 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400
JBrowse link
G Socs2 suppressor of cytokine signaling 2 IAGP MGI PMID:22562833 NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042
JBrowse link
G Stat1 signal transducer and activator of transcription 1 IAGP MGI PMID:12370359 PMID:14670297 NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024
JBrowse link
G Stat3 signal transducer and activator of transcription 3 IAGP MGI PMID:12571365 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:16275384 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826
JBrowse link
G Stx11 syntaxin 11 IAGP MGI PMID:23160464 NCBI chr10:12,813,961...12,840,242
Ensembl chr10:12,813,953...12,840,042
JBrowse link
G Tlr7 toll-like receptor 7 IAGP MGI PMID:35477763 NCBI chr  X:166,086,376...166,113,570
Ensembl chr  X:166,087,925...166,113,554
JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 IAGP MGI PMID:24498102 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405
JBrowse link
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b IAGP MGI PMID:15589175 NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:21411755 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Vav1 vav 1 oncogene IAGP MGI PMID:20009105 NCBI chr17:57,586,080...57,636,236
Ensembl chr17:57,586,100...57,635,031
JBrowse link
G Zc3h12c zinc finger CCCH type containing 12C IAGP MGI PMID:31126966 NCBI chr 9:52,020,869...52,080,028
Ensembl chr 9:52,022,644...52,079,872
JBrowse link
G Zg16 zymogen granule protein 16 IAGP MGI PMID:27849619 NCBI chr 7:126,649,328...126,651,847
Ensembl chr 7:126,649,328...126,686,500
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 17065
    immune system phenotype 5763
      abnormal immune system physiology 3496
        abnormal immune serum protein physiology 1479
          abnormal cytokine level 606
            increased cytokine level 102
              increased interferon level 90
                increased circulating interferon-alpha level 14
                increased circulating interferon-beta level 20
                increased circulating interferon-gamma level 65
Path 2
Term Annotations click to browse term
  mammalian phenotype 17065
    homeostasis/metabolism phenotype 7909
      abnormal homeostasis 7051
        abnormal protein level 2371
          abnormal intercellular signaling peptide or protein level 621
            abnormal cytokine level 606
              abnormal interferon level 186
                increased interferon level 90
                  increased circulating interferon-alpha level 14
                  increased circulating interferon-beta level 20
                  increased circulating interferon-gamma level 65
paths to the root