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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal endocrine pancreas secretion
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Accession:MP:0014195 term browser browse the term
Definition:anomaly in the synthesis and/or release of any of the hormones produced by different types of cells in the islets of Langerhans of the endocrine pancreas and secreted directly into the blood stream to regulate blood glucose homeostasis; these hormones include glucagon secreted by alpha cells, insulin and amylin (also known as Islet Amyloid Polypeptide or IAPP) co-secreted by beta cells, somatostatin secreted by delta cells, gherlin secreted by epsilon cells, and pancreatic polypeptide secreted by PP cells (also known as F cells
Synonyms:exact_synonym: abnormal endocrine pancreatic secretion


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  mammalian phenotype 0
    endocrine/exocrine gland phenotype 0
      abnormal gland physiology 0
        abnormal pancreas physiology 0
          abnormal pancreas secretion 0
            abnormal endocrine pancreas secretion 0
              abnormal amylin secretion + 0
              abnormal glucagon secretion + 0
              abnormal insulin secretion + 0
              abnormal pancreatic ghrelin secretion 0
              abnormal pancreatic polypeptide secretion 0
              abnormal pancreatic somatostatin secretion 0
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