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Pathways

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal platelet alpha-granule morphology
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Accession:MP:0014060 term browser browse the term
Definition:any structural anomaly of the most abundant secretory organelle found in blood platelets, and which store adhesive molecules such as von Willebrand factor and fibrinogen, growth factors and inflammatory and angiogenic mediators, which play crucial roles in inflammatory responses and tumor genesis



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abnormal platelet alpha-granule morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S WF/NHsd IAGP compared to Hsd:WI RGD PMID:2040691 RGD:11531117

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  mammalian phenotype 5380
    hematopoietic system phenotype 244
      abnormal hematopoietic system morphology/development 224
        abnormal hematopoietic cell morphology 180
          abnormal myeloid cell morphology 102
            abnormal platelet morphology 13
              abnormal platelet alpha-granule morphology 1
                abnormal platelet alpha-granule number + 0
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