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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal platelet alpha-granule morphology
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Accession:MP:0014060 term browser browse the term
Definition:any structural anomaly of the most abundant secretory organelle found in blood platelets, and which store adhesive molecules such as von Willebrand factor and fibrinogen, growth factors and inflammatory and angiogenic mediators, which play crucial roles in inflammatory responses and tumor genesis



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  mammalian phenotype 0
    hematopoietic system phenotype 0
      abnormal hematopoietic system morphology/development 0
        abnormal hematopoietic cell morphology 0
          abnormal myeloid cell morphology 0
            abnormal platelet morphology 0
              abnormal platelet alpha-granule morphology 0
                abnormal platelet alpha-granule number + 0
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