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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased T-helper cell number
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Accession:MP:0013764 term browser browse the term
Definition:reduction in the number of an effector T cell that provides help in the form of secreted cytokines to other immune cells
Synonyms:exact_synonym: decreased helper T lymphocyte number


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decreased T-helper cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd38 CD38 antigen IEA MGI NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658 		JBrowse link
G Dph6 diphthamine biosynthesis 6 IEA MGI NCBI chr 2:114,346,897...114,485,518
Ensembl chr 2:114,346,897...114,485,445 		JBrowse link
G Gda guanine deaminase IEA MGI NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809 		JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase IEA MGI NCBI chr13:32,003,566...32,522,744
Ensembl chr13:32,003,562...32,522,723 		JBrowse link
G Hbs1l Hbs1-like (S. cerevisiae) IEA MGI NCBI chr10:21,171,876...21,244,788
Ensembl chr10:21,171,878...21,244,797 		JBrowse link
G Krtap8-1 keratin associated protein 8-1 IEA MGI NCBI chr16:89,284,262...89,284,840
Ensembl chr16:89,284,267...89,284,840 		JBrowse link
G Sik3 SIK family kinase 3 IEA MGI NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492 		JBrowse link
G Tmem126a transmembrane protein 126A IEA MGI NCBI chr 7:90,099,908...90,106,411
Ensembl chr 7:90,099,908...90,106,437 		JBrowse link
G Vps13a vacuolar protein sorting 13A IEA MGI NCBI chr19:16,592,730...16,758,433
Ensembl chr19:16,592,730...16,758,297 		JBrowse link
decreased T follicular helper cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper transcription factor, ATF-like IAGP MGI PMID:20421391 NCBI chr12:85,733,494...85,755,861
Ensembl chr12:85,733,443...85,755,861 		JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 IAGP MGI PMID:21636294 PMID:23027924 PMID:23455674 PMID:23980208 NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602 		JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 IAGP MGI PMID:23997217 NCBI chr 6:128,386,407...128,401,873
Ensembl chr 6:128,386,407...128,401,894 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IAGP MGI PMID:20826752 NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:20826752 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Tnfsf15 tumor necrosis factor (ligand) superfamily, member 15 IAGP MGI PMID:24140642 NCBI chr 4:63,642,837...63,663,296
Ensembl chr 4:63,642,840...63,663,350 		JBrowse link
decreased T helper 1 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 antigen IAGP MGI PMID:20639491 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495 		JBrowse link
G Cd4 CD4 antigen IAGP MGI PMID:35304452 NCBI chr 6:124,841,656...124,865,210
Ensembl chr 6:124,841,655...124,865,184 		JBrowse link
G Cd5 CD5 antigen IAGP MGI PMID:22904299 NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366 		JBrowse link
G Il1r1 interleukin 1 receptor, type I IAGP MGI PMID:30662948 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417 		JBrowse link
G Nkg7 natural killer cell group 7 sequence IAGP MGI PMID:32839608 NCBI chr 7:43,086,562...43,087,670
Ensembl chr 7:43,086,497...43,087,673 		JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 IAGP MGI PMID:24792914 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199 		JBrowse link
G Tbx21 T-box 21 IAGP MGI PMID:11786644 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 IAGP MGI PMID:30662948 NCBI chr  X:95,290,807...95,337,044
Ensembl chr  X:95,290,809...95,337,044 		JBrowse link
G Zranb1 zinc finger, RAN-binding domain containing 1 IAGP MGI PMID:26808229 NCBI chr 7:132,532,905...132,588,127
Ensembl chr 7:132,532,871...132,588,120 		JBrowse link
decreased T-helper 17 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT rich interactive domain 5A (MRF1-like) IAGP MGI PMID:23676272 NCBI chr 1:36,346,814...36,363,117
Ensembl chr 1:36,346,814...36,363,110 		JBrowse link
G B9d2 B9 protein domain 2 IAGP MGI PMID:21435587 NCBI chr 7:25,380,205...25,385,987
Ensembl chr 7:25,380,205...25,385,983 		JBrowse link
G Batf basic leucine zipper transcription factor, ATF-like IAGP MGI PMID:20421391 NCBI chr12:85,733,494...85,755,861
Ensembl chr12:85,733,443...85,755,861 		JBrowse link
G Cd274 CD274 antigen IAGP MGI PMID:21061440 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495 		JBrowse link
G Cd5 CD5 antigen IAGP MGI PMID:22904299 NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366 		JBrowse link
G Elavl1 ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) IAGP MGI PMID:24166976 NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413 		JBrowse link
G Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 IAGP MGI PMID:22550081 NCBI chr 9:107,491,324...107,512,542
Ensembl chr 9:107,491,324...107,512,566 		JBrowse link
G Il1r1 interleukin 1 receptor, type I IAGP MGI PMID:30662948 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417 		JBrowse link
G Mir155 microRNA 155 IAGP MGI PMID:26163372 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Pdcd1 programmed cell death 1 IAGP MGI PMID:22949674 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 IAGP MGI PMID:32709928 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099 		JBrowse link
G Siglech sialic acid binding Ig-like lectin H IAGP MGI PMID:22177923 NCBI chr 7:55,417,916...55,429,196
Ensembl chr 7:55,417,926...55,428,673 		JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 IAGP MGI PMID:24792914 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 IAGP MGI PMID:17363300 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IAGP MGI PMID:21435587 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:21435587 PMID:24166976 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 IAGP MGI PMID:30662948 NCBI chr  X:95,290,807...95,337,044
Ensembl chr  X:95,290,809...95,337,044 		JBrowse link
G Zranb1 zinc finger, RAN-binding domain containing 1 IAGP MGI PMID:26808229 NCBI chr 7:132,532,905...132,588,127
Ensembl chr 7:132,532,871...132,588,120 		JBrowse link
decreased T-helper 2 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chi3l1 chitinase 3 like 1 IAGP MGI PMID:19414556 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919 		JBrowse link
G Ebi3 Epstein-Barr virus induced gene 3 IAGP MGI PMID:12482940 NCBI chr17:56,259,623...56,264,022
Ensembl chr17:56,259,640...56,264,022 		JBrowse link
G Gata3 GATA binding protein 3 IAGP MGI PMID:15475959 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845 		JBrowse link
G Il13 interleukin 13 IAGP MGI PMID:9768762 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il25 interleukin 25 IAGP MGI PMID:25888259 NCBI chr14:55,170,152...55,173,294
Ensembl chr14:55,170,152...55,173,294 		JBrowse link
G Il4ra interleukin 4 receptor, alpha IAGP MGI PMID:21460847 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646 		JBrowse link
G Nfatc2ip nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein IAGP MGI PMID:20133688 NCBI chr 7:125,982,025...125,995,909
Ensembl chr 7:125,982,026...125,995,909 		JBrowse link
G Pdcd1 programmed cell death 1 IAGP MGI PMID:22949674 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 IAGP MGI PMID:32709928 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:21460847 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16438
    hematopoietic system phenotype 5334
      abnormal hematopoietic system morphology/development 4874
        abnormal hematopoietic cell morphology 4051
          abnormal hematopoietic cell number 2909
            abnormal leukocyte cell number 2417
              decreased leukocyte cell number 1588
                decreased lymphocyte cell number 1234
                  decreased T cell number 756
                    decreased T-helper cell number 43
                      decreased T follicular helper cell number 6
                      decreased T helper 1 cell number 9
                      decreased T-helper 17 cell number 18
                      decreased T-helper 2 cell number 10
Path 2
Term Annotations click to browse term
  mammalian phenotype 16438
    hematopoietic system phenotype 5334
      abnormal hematopoietic system morphology/development 4874
        abnormal hematopoietic cell morphology 4051
          abnormal leukocyte morphology 2695
            abnormal mononuclear cell morphology 2182
              abnormal lymphocyte morphology 1768
                abnormal T cell morphology 1129
                  abnormal T cell number 1036
                    abnormal effector T cell number 241
                      abnormal T-helper cell number 134
                        decreased T-helper cell number 43
                          decreased T follicular helper cell number 6
                          decreased T helper 1 cell number 9
                          decreased T-helper 17 cell number 18
                          decreased T-helper 2 cell number 10
paths to the root