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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal T-helper cell number
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Accession:MP:0013761 term browser browse the term
Definition:anomaly in the number of an effector T cell that provides help in the form of secreted cytokines to other immune cells
Synonyms:exact_synonym: abnormal helper T lymphocyte number


show annotations for term's descendants           Sort by:
abnormal T-helper 2 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chil1 chitinase-like 1 IAGP MGI PMID:19414556 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919 		JBrowse link
decreased effector memory T-helper cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Asb2 ankyrin repeat and SOCS box-containing 2 IEA MGI NCBI chr12:103,287,401...103,322,260
Ensembl chr12:103,287,401...103,322,260 		JBrowse link
G Card11 caspase recruitment domain family, member 11 IEA MGI NCBI chr 5:140,858,754...140,986,351
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Cd38 CD38 antigen IEA MGI NCBI chr 5:44,026,151...44,069,716
Ensembl chr 5:44,025,895...44,069,717 		JBrowse link
G Duoxa2 dual oxidase maturation factor 2 IEA MGI NCBI chr 2:122,129,381...122,133,366
Ensembl chr 2:122,129,381...122,133,366 		JBrowse link
G Flt3 FMS-like tyrosine kinase 3 IEA MGI NCBI chr 5:147,267,551...147,337,299
Ensembl chr 5:147,267,551...147,337,299 		JBrowse link
G Hcar1 hydrocarboxylic acid receptor 1 IEA MGI NCBI chr 5:124,014,802...124,018,066
Ensembl chr 5:124,014,799...124,018,083 		JBrowse link
G Mir155 microRNA 155 IAGP MGI PMID:26163372 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Sik3 SIK family kinase 3 IEA MGI NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 IAGP MGI PMID:26163372 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400 		JBrowse link
G Tet1 tet methylcytosine dioxygenase 1 IAGP MGI PMID:35304452 NCBI chr10:62,640,349...62,723,242
Ensembl chr10:62,640,349...62,744,775 		JBrowse link
G Tet2 tet methylcytosine dioxygenase 2 IAGP MGI PMID:35304452 NCBI chr 3:133,169,438...133,250,882
Ensembl chr 3:133,169,440...133,250,900 		JBrowse link
G Tet3 tet methylcytosine dioxygenase 3 IAGP MGI PMID:35304452 NCBI chr 6:83,339,355...83,434,190
Ensembl chr 6:83,339,355...83,436,066 		JBrowse link
G Tmem60 transmembrane protein 60 IEA MGI NCBI chr 5:21,087,451...21,091,868
Ensembl chr 5:21,087,189...21,091,868 		JBrowse link
G Trim9 tripartite motif-containing 9 IEA MGI NCBI chr12:70,291,307...70,394,531
Ensembl chr12:70,291,307...70,394,388 		JBrowse link
decreased KLRG1-positive T-helper cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sik3 SIK family kinase 3 IEA MGI NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492 		JBrowse link
G Tmem127 transmembrane protein 127 IEA MGI NCBI chr 2:127,089,868...127,103,028
Ensembl chr 2:127,089,828...127,103,027 		JBrowse link
decreased T follicular helper cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Batf basic leucine zipper transcription factor, ATF-like IAGP MGI PMID:20421391 NCBI chr12:85,733,494...85,755,861
Ensembl chr12:85,733,443...85,755,861 		JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 IAGP MGI PMID:21636294 PMID:23027924 PMID:23455674 PMID:23980208 NCBI chr16:23,783,800...23,807,623
Ensembl chr16:23,783,802...23,807,602 		JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 IAGP MGI PMID:23997217 NCBI chr 6:128,386,407...128,401,873
Ensembl chr 6:128,386,407...128,401,894 		JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta IAGP MGI PMID:20826752 NCBI chr 4:149,733,625...149,787,023
Ensembl chr 4:149,733,625...149,787,028 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:20826752 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Tnfsf15 tumor necrosis factor (ligand) superfamily, member 15 IAGP MGI PMID:24140642 NCBI chr 4:63,642,837...63,663,296
Ensembl chr 4:63,642,840...63,663,350 		JBrowse link
decreased T helper 1 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd274 CD274 antigen IAGP MGI PMID:20639491 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495 		JBrowse link
G Cd4 CD4 antigen IAGP MGI PMID:35304452 NCBI chr 6:124,841,656...124,865,210
Ensembl chr 6:124,841,655...124,865,184 		JBrowse link
G Cd5 CD5 antigen IAGP MGI PMID:22904299 NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366 		JBrowse link
G Il1r1 interleukin 1 receptor, type I IAGP MGI PMID:30662948 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417 		JBrowse link
G Nkg7 natural killer cell group 7 sequence IAGP MGI PMID:32839608 NCBI chr 7:43,086,562...43,087,670
Ensembl chr 7:43,086,497...43,087,673 		JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 IAGP MGI PMID:24792914 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199 		JBrowse link
G Tbx21 T-box 21 IAGP MGI PMID:11786644 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 IAGP MGI PMID:30662948 NCBI chr  X:95,290,807...95,337,044
Ensembl chr  X:95,290,809...95,337,044 		JBrowse link
G Zranb1 zinc finger, RAN-binding domain containing 1 IAGP MGI PMID:26808229 NCBI chr 7:132,532,905...132,588,127
Ensembl chr 7:132,532,871...132,588,120 		JBrowse link
decreased T-helper 17 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arid5a AT rich interactive domain 5A (MRF1-like) IAGP MGI PMID:23676272 NCBI chr 1:36,346,814...36,363,117
Ensembl chr 1:36,346,814...36,363,110 		JBrowse link
G B9d2 B9 protein domain 2 IAGP MGI PMID:21435587 NCBI chr 7:25,380,205...25,385,987
Ensembl chr 7:25,380,205...25,385,983 		JBrowse link
G Batf basic leucine zipper transcription factor, ATF-like IAGP MGI PMID:20421391 NCBI chr12:85,733,494...85,755,861
Ensembl chr12:85,733,443...85,755,861 		JBrowse link
G Cd274 CD274 antigen IAGP MGI PMID:21061440 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495 		JBrowse link
G Cd5 CD5 antigen IAGP MGI PMID:22904299 NCBI chr19:10,695,471...10,716,390
Ensembl chr19:10,694,480...10,716,366 		JBrowse link
G Elavl1 ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) IAGP MGI PMID:24166976 NCBI chr 8:4,334,781...4,375,104
Ensembl chr 8:4,335,382...4,375,413 		JBrowse link
G Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 IAGP MGI PMID:22550081 NCBI chr 9:107,491,324...107,512,617
Ensembl chr 9:107,491,324...107,512,566 		JBrowse link
G Il1r1 interleukin 1 receptor, type I IAGP MGI PMID:30662948 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417 		JBrowse link
G Mir155 microRNA 155 IAGP MGI PMID:26163372 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Pdcd1 programmed cell death 1 IAGP MGI PMID:22949674 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 IAGP MGI PMID:32709928 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099 		JBrowse link
G Siglech sialic acid binding Ig-like lectin H IAGP MGI PMID:22177923 NCBI chr 7:55,417,916...55,429,196
Ensembl chr 7:55,417,926...55,428,673 		JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 IAGP MGI PMID:24792914 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 IAGP MGI PMID:17363300 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IAGP MGI PMID:21435587 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:21435587 PMID:24166976 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 IAGP MGI PMID:30662948 NCBI chr  X:95,290,807...95,337,044
Ensembl chr  X:95,290,809...95,337,044 		JBrowse link
G Zranb1 zinc finger, RAN-binding domain containing 1 IAGP MGI PMID:26808229 NCBI chr 7:132,532,905...132,588,127
Ensembl chr 7:132,532,871...132,588,120 		JBrowse link
decreased T-helper 2 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chil1 chitinase-like 1 IAGP MGI PMID:19414556 NCBI chr 1:134,109,894...134,117,769
Ensembl chr 1:134,109,914...134,117,919 		JBrowse link
G Ebi3 Epstein-Barr virus induced gene 3 IAGP MGI PMID:12482940 NCBI chr17:56,259,623...56,264,022
Ensembl chr17:56,259,640...56,264,022 		JBrowse link
G Gata3 GATA binding protein 3 IAGP MGI PMID:15475959 NCBI chr 2:9,861,889...9,892,762
Ensembl chr 2:9,861,889...9,894,845 		JBrowse link
G Il13 interleukin 13 IAGP MGI PMID:9768762 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il25 interleukin 25 IAGP MGI PMID:25888259 NCBI chr14:55,170,152...55,173,294
Ensembl chr14:55,170,152...55,173,294 		JBrowse link
G Il4ra interleukin 4 receptor, alpha IAGP MGI PMID:21460847 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646 		JBrowse link
G Nfatc2ip nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein IAGP MGI PMID:20133688 NCBI chr 7:125,982,025...125,995,966
Ensembl chr 7:125,982,026...125,995,909 		JBrowse link
G Pdcd1 programmed cell death 1 IAGP MGI PMID:22949674 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Pgam1 phosphoglycerate mutase 1 IAGP MGI PMID:32709928 NCBI chr19:41,900,310...41,907,104
Ensembl chr19:41,900,362...41,907,099 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 IAGP MGI PMID:21460847 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
decreased T-helper cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd38 CD38 antigen IEA MGI NCBI chr 5:44,026,151...44,069,716
Ensembl chr 5:44,025,895...44,069,717 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658 		JBrowse link
G Dph6 diphthamine biosynthesis 6 IEA MGI NCBI chr 2:114,346,897...114,485,518
Ensembl chr 2:114,346,897...114,485,445 		JBrowse link
G Gda guanine deaminase IEA MGI NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809 		JBrowse link
G Gmds GDP-mannose 4, 6-dehydratase IEA MGI NCBI chr13:32,003,566...32,522,744
Ensembl chr13:32,003,562...32,522,723 		JBrowse link
G Hbs1l Hbs1-like (S. cerevisiae) IEA MGI NCBI chr10:21,171,876...21,244,788
Ensembl chr10:21,171,878...21,244,797 		JBrowse link
G Krtap8-1 keratin associated protein 8-1 IEA MGI NCBI chr16:89,284,262...89,284,840
Ensembl chr16:89,284,267...89,284,840 		JBrowse link
G Sik3 SIK family kinase 3 IEA MGI NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492 		JBrowse link
G Tmem126a transmembrane protein 126A IEA MGI NCBI chr 7:90,099,908...90,106,411
Ensembl chr 7:90,099,908...90,106,437 		JBrowse link
G Vps13a vacuolar protein sorting 13A IEA MGI NCBI chr19:16,592,730...16,758,433
Ensembl chr19:16,592,730...16,758,297 		JBrowse link
increased effector memory T-helper cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 3425401B19Rik RIKEN cDNA 3425401B19 gene IEA MGI NCBI chr14:32,381,075...32,430,049
Ensembl chr14:32,381,076...32,407,250 		JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B IEA MGI NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515 		JBrowse link
G Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 IEA MGI NCBI chr 4:32,238,413...32,586,109
Ensembl chr 4:32,238,804...32,586,108 		JBrowse link
G Bcap31 B cell receptor associated protein 31 IAGP MGI PMID:28333124 NCBI chr  X:72,729,784...72,761,421
Ensembl chr  X:72,729,784...72,759,781 		JBrowse link
G Churc1 churchill domain containing 1 IEA MGI NCBI chr12:76,812,312...76,829,954
Ensembl chr12:76,812,312...76,829,954 		JBrowse link
G Cnpy2 canopy FGF signaling regulator 2 IEA MGI NCBI chr10:128,157,972...128,163,056
Ensembl chr10:128,158,328...128,163,422 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658 		JBrowse link
G Copa coatomer protein complex subunit alpha IAGP MGI PMID:32198142 NCBI chr 1:171,909,885...171,949,899
Ensembl chr 1:171,910,096...171,949,897 		JBrowse link
G Cxcr2 chemokine (C-X-C motif) receptor 2 IEA MGI NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,148...74,200,405 		JBrowse link
G Dph6 diphthamine biosynthesis 6 IEA MGI NCBI chr 2:114,346,897...114,485,518
Ensembl chr 2:114,346,897...114,485,445 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:27410049 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Gda guanine deaminase IEA MGI NCBI chr19:21,368,671...21,450,025
Ensembl chr19:21,368,671...21,450,809 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 IAGP MGI PMID:24696448 NCBI chr10:119,977,553...120,038,035
Ensembl chr10:119,977,553...120,038,035 		JBrowse link
G Nipsnap3a nipsnap homolog 3A IEA MGI NCBI chr 4:52,989,284...53,000,854
Ensembl chr 4:52,989,272...53,001,162 		JBrowse link
G Nub1 negative regulator of ubiquitin-like proteins 1 IEA MGI NCBI chr 5:24,890,813...24,915,376
Ensembl chr 5:24,890,530...24,915,376 		JBrowse link
G Nup210 nucleoporin 210 IAGP MGI PMID:29736031 NCBI chr 6:90,990,049...91,095,920
Ensembl chr 6:90,990,050...91,093,811 		JBrowse link
G Pdcd1 programmed cell death 1 IAGP MGI PMID:27410049 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Pdgfc platelet-derived growth factor, C polypeptide IEA MGI NCBI chr 3:80,943,723...81,121,347
Ensembl chr 3:80,943,723...81,121,347 		JBrowse link
G Pepd peptidase D IEA MGI NCBI chr 7:34,611,832...34,744,133
Ensembl chr 7:34,611,804...34,744,133 		JBrowse link
G Prdm14 PR domain containing 14 IEA MGI NCBI chr 1:13,183,652...13,197,387
Ensembl chr 1:13,183,681...13,197,387 		JBrowse link
G Rnf128 ring finger protein 128 IEA MGI NCBI chr  X:138,464,089...138,573,894
Ensembl chr  X:138,464,065...138,573,894 		JBrowse link
G Sik3 SIK family kinase 3 IEA MGI NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492 		JBrowse link
G Spred1 sprouty protein with EVH-1 domain 1, related sequence IEA MGI NCBI chr 2:116,951,552...117,012,760
Ensembl chr 2:116,951,855...117,012,760 		JBrowse link
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 IAGP MGI PMID:35464428 NCBI chr10:18,876,658...18,891,158
Ensembl chr10:18,876,658...18,891,405 		JBrowse link
G Ydjc YdjC homolog (bacterial) IEA MGI NCBI chr16:16,964,813...16,966,721
Ensembl chr16:16,962,485...16,978,565 		JBrowse link
increased KLRG1-positive T-helper cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpc1b actin related protein 2/3 complex, subunit 1B IEA MGI NCBI chr 5:145,051,066...145,064,996
Ensembl chr 5:145,051,025...145,067,515 		JBrowse link
G Cog6 component of oligomeric golgi complex 6 IEA MGI NCBI chr 3:52,889,544...52,924,644
Ensembl chr 3:52,889,296...52,924,658 		JBrowse link
G Dph6 diphthamine biosynthesis 6 IEA MGI NCBI chr 2:114,346,897...114,485,518
Ensembl chr 2:114,346,897...114,485,445 		JBrowse link
G Sik3 SIK family kinase 3 IEA MGI NCBI chr 9:45,924,099...46,135,492
Ensembl chr 9:45,924,118...46,135,492 		JBrowse link
G Zfp616 zinc finger protein 616 IEA MGI NCBI chr11:73,951,723...73,978,127
Ensembl chr11:73,960,781...73,978,118 		JBrowse link
increased T follicular helper cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40 CD40 antigen IAGP MGI PMID:30013024 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:31296356 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Id3 inhibitor of DNA binding 3 IAGP MGI PMID:21857655 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066 		JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 (G1m marker) IAGP MGI PMID:30013024 NCBI chr12:113,290,161...113,294,143
Ensembl chr12:113,288,860...113,294,143 		JBrowse link
G Ikzf4 IKAROS family zinc finger 4 IAGP MGI PMID:31296356 NCBI chr10:128,466,708...128,505,668
Ensembl chr10:128,466,712...128,505,227 		JBrowse link
G Mir146 microRNA 146 IAGP MGI PMID:30013024 NCBI chr11:43,265,224...43,265,288
Ensembl chr11:43,265,224...43,265,288 		JBrowse link
G Mir146b microRNA 146b IAGP MGI PMID:30013024 NCBI chr19:46,331,201...46,331,309
Ensembl chr19:46,331,201...46,331,309 		JBrowse link
G Pnp purine-nucleoside phosphorylase IEA MGI NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,202,694 		JBrowse link
G Prdm1 PR domain containing 1, with ZNF domain IAGP MGI PMID:21948081 NCBI chr10:44,313,170...44,404,548
Ensembl chr10:44,313,173...44,404,497 		JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:20826752 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560 		JBrowse link
G Rc3h1 RING CCCH (C3H) domains 1 IAGP MGI PMID:22700722 PMID:23583642 PMID:23583643 NCBI chr 1:160,733,981...160,802,546
Ensembl chr 1:160,733,988...160,802,548 		JBrowse link
G Rc3h2 ring finger and CCCH-type zinc finger domains 2 IAGP MGI PMID:23583642 PMID:23583643 NCBI chr 2:37,260,078...37,313,007
Ensembl chr 2:37,260,081...37,312,915 		JBrowse link
G Rhoa ras homolog family member A IAGP MGI PMID:29398449 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133 		JBrowse link
G Rnaseh2b ribonuclease H2, subunit B IAGP MGI PMID:35477763 NCBI chr14:62,569,517...62,610,445
Ensembl chr14:62,530,038...62,610,441 		JBrowse link
G Scarf1 scavenger receptor class F, member 1 IAGP MGI PMID:23892722 NCBI chr11:75,404,310...75,417,408
Ensembl chr11:75,404,366...75,417,408 		JBrowse link
G Tlr7 toll-like receptor 7 IAGP MGI PMID:35477763 NCBI chr  X:166,086,376...166,113,570
Ensembl chr  X:166,087,925...166,113,554 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:20826752 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 IAGP MGI PMID:21606507 NCBI chr11:54,801,613...54,853,766
Ensembl chr11:54,801,611...54,853,743 		JBrowse link
increased T-helper 1 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 a disintegrin and metallopeptidase domain 17 IAGP MGI PMID:25902485 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633 		JBrowse link
G B2m beta-2 microglobulin IAGP MGI PMID:17562770 NCBI chr 2:121,978,168...121,983,563
Ensembl chr 2:121,978,167...121,983,564 		JBrowse link
G B9d2 B9 protein domain 2 IAGP MGI PMID:21435587 NCBI chr 7:25,380,205...25,385,987
Ensembl chr 7:25,380,205...25,385,983 		JBrowse link
G Dusp14 dual specificity phosphatase 14 IAGP MGI PMID:24403530 NCBI chr11:83,938,859...83,960,088
Ensembl chr11:83,938,867...83,960,087 		JBrowse link
G Egfr epidermal growth factor receptor IAGP MGI PMID:25902485 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Gata3 GATA binding protein 3 IAGP MGI PMID:15475959 NCBI chr 2:9,861,889...9,892,762
Ensembl chr 2:9,861,889...9,894,845 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:23966625 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Il9r interleukin 9 receptor IAGP MGI PMID:19433802 NCBI chr11:32,137,544...32,155,283
Ensembl chr11:32,137,541...32,150,279 		JBrowse link
G Itgb2 integrin beta 2 IAGP MGI PMID:14634077 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Lgals9 lectin, galactose binding, soluble 9 IAGP MGI PMID:18282810 NCBI chr11:78,853,805...78,875,750
Ensembl chr11:78,853,800...78,875,772 		JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IAGP MGI PMID:34420035 NCBI chr18:70,701,298...70,761,769
Ensembl chr18:70,701,260...70,759,202 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 IAGP MGI PMID:19501001 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 IAGP MGI PMID:21468021 NCBI chr 2:56,996,845...57,014,018
Ensembl chr 2:56,996,842...57,014,015 		JBrowse link
G Nup210 nucleoporin 210 IAGP MGI PMID:30323813 NCBI chr 6:90,990,049...91,095,920
Ensembl chr 6:90,990,050...91,093,811 		JBrowse link
G Pdcd1 programmed cell death 1 IAGP MGI PMID:22949674 NCBI chr 1:93,966,027...93,980,278
Ensembl chr 1:93,966,027...93,980,278 		JBrowse link
G Reg3g regenerating islet-derived 3 gamma IAGP MGI PMID:21998396 NCBI chr 6:78,443,252...78,445,857
Ensembl chr 6:78,443,252...78,445,855 		JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 IAGP MGI PMID:25902485 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586 		JBrowse link
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) IAGP MGI PMID:17562770 NCBI chr17:34,406,530...34,416,199
Ensembl chr17:34,406,527...34,416,199 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IAGP MGI PMID:11342667 PMID:21435587 PMID:23569233 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 IAGP MGI PMID:21435587 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Tnfsf12 tumor necrosis factor (ligand) superfamily, member 12 IAGP MGI PMID:16325585 NCBI chr11:69,577,066...69,586,924
Ensembl chr11:69,577,076...69,586,675 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator IAGP MGI PMID:21683627 NCBI chr19:3,985,171...3,999,340
Ensembl chr19:3,985,186...3,999,340 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 IAGP MGI PMID:30662948 NCBI chr  X:95,290,807...95,337,044
Ensembl chr  X:95,290,809...95,337,044 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 IAGP MGI PMID:21727190 NCBI chr 3:100,732,765...100,804,238
Ensembl chr 3:100,732,775...100,804,238 		JBrowse link
increased T-helper 17 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ackr4 atypical chemokine receptor 4 IAGP MGI PMID:20562329 NCBI chr 9:103,974,881...104,003,842
Ensembl chr 9:103,961,356...104,004,132 		JBrowse link
G Adam17 a disintegrin and metallopeptidase domain 17 IAGP MGI PMID:25902485 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 IAGP MGI PMID:23500093 NCBI chr17:93,505,673...93,513,969
Ensembl chr17:93,506,445...93,513,965 		JBrowse link
G Bsg basigin IAGP MGI PMID:25891969 NCBI chr10:79,540,192...79,547,813
Ensembl chr10:79,540,325...79,547,803 		JBrowse link
G Dusp14 dual specificity phosphatase 14 IAGP MGI PMID:24403530 NCBI chr11:83,938,859...83,960,088
Ensembl chr11:83,938,867...83,960,087 		JBrowse link
G Egfr epidermal growth factor receptor IAGP MGI PMID:25902485 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Entpd7 ectonucleoside triphosphate diphosphohydrolase 7 IAGP MGI PMID:23241884 NCBI chr19:43,678,128...43,722,292
Ensembl chr19:43,678,111...43,722,136 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:23966625 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Ier3 immediate early response 3 IAGP MGI PMID:22550081 NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815 		JBrowse link
G Il17ra interleukin 17 receptor A IAGP MGI PMID:22951726 NCBI chr 6:120,440,143...120,460,692
Ensembl chr 6:120,440,208...120,464,520 		JBrowse link
G Nfil3 nuclear factor, interleukin 3, regulated IAGP MGI PMID:24442434 NCBI chr13:53,121,245...53,136,914
Ensembl chr13:53,121,245...53,135,109 		JBrowse link
G Rag2 recombination activating gene 2 IAGP MGI PMID:17363300 NCBI chr 2:101,455,057...101,462,873
Ensembl chr 2:101,455,063...101,462,874 		JBrowse link
G Siglech sialic acid binding Ig-like lectin H IAGP MGI PMID:22177923 NCBI chr 7:55,417,916...55,429,196
Ensembl chr 7:55,417,926...55,428,673 		JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 IAGP MGI PMID:25902485 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586 		JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 IAGP MGI PMID:23633022 NCBI chr12:87,351,832...87,435,129
Ensembl chr12:87,351,832...87,435,129 		JBrowse link
G Unc93b1 unc-93 homolog B1, TLR signaling regulator IAGP MGI PMID:21683627 NCBI chr19:3,985,171...3,999,340
Ensembl chr19:3,985,186...3,999,340 		JBrowse link
G Vsig4 V-set and immunoglobulin domain containing 4 IAGP MGI PMID:30662948 NCBI chr  X:95,290,807...95,337,044
Ensembl chr  X:95,290,809...95,337,044 		JBrowse link
G Vtcn1 V-set domain containing T cell activation inhibitor 1 IAGP MGI PMID:21727190 NCBI chr 3:100,732,765...100,804,238
Ensembl chr 3:100,732,775...100,804,238 		JBrowse link
G Zc3h12d zinc finger CCCH type containing 12D IAGP MGI PMID:24415781 NCBI chr10:7,708,087...7,746,161
Ensembl chr10:7,708,234...7,746,160 		JBrowse link
increased T-helper 2 cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam17 a disintegrin and metallopeptidase domain 17 IAGP MGI PMID:25902485 NCBI chr12:21,373,510...21,423,633
Ensembl chr12:21,373,510...21,423,633 		JBrowse link
G Apoe apolipoprotein E IAGP MGI PMID:9541503 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Egfr epidermal growth factor receptor IAGP MGI PMID:25902485 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158 		JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 IAGP MGI PMID:18066066 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912 		JBrowse link
G Il17b interleukin 17B IAGP MGI PMID:25888259 NCBI chr18:61,821,006...61,825,609
Ensembl chr18:61,817,958...61,825,609 		JBrowse link
G Irf1 interferon regulatory factor 1 IAGP MGI PMID:9379011 NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200 		JBrowse link
G Lat linker for activation of T cells IAGP MGI PMID:12065839 PMID:23793062 NCBI chr 7:125,962,999...125,968,877
Ensembl chr 7:125,962,996...125,968,742 		JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IAGP MGI PMID:34420035 NCBI chr18:70,701,298...70,761,769
Ensembl chr18:70,701,260...70,759,202 		JBrowse link
G Mir155 microRNA 155 IAGP MGI PMID:17463290 NCBI chr16:84,511,028...84,511,092
Ensembl chr16:84,511,028...84,511,092 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IAGP MGI PMID:14764732 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 IAGP MGI PMID:22547705 NCBI chr18:38,551,960...38,598,250
Ensembl chr18:38,543,449...38,598,356 		JBrowse link
G Polb polymerase (DNA directed), beta IAGP MGI PMID:24388753 NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451 		JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 IAGP MGI PMID:19107198 NCBI chr 5:103,573,058...103,746,227
Ensembl chr 5:103,573,058...103,746,169 		JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 IAGP MGI PMID:25902485 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586 		JBrowse link
G Tbx21 T-box 21 IAGP MGI PMID:11786644 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
increased T-helper cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa5 annexin A5 IAGP MGI PMID:22692895 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043 		JBrowse link
G Anxa6 annexin A6 IAGP MGI PMID:22692895 NCBI chr11:54,869,779...54,924,297
Ensembl chr11:54,869,934...54,924,271 		JBrowse link
G Card11 caspase recruitment domain family, member 11 IEA MGI NCBI chr 5:140,858,754...140,986,351
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Col10a1 collagen, type X, alpha 1 IAGP MGI PMID:22692895 NCBI chr10:34,265,977...34,273,081
Ensembl chr10:34,265,977...34,273,081 		JBrowse link
G Duoxa2 dual oxidase maturation factor 2 IEA MGI NCBI chr 2:122,129,381...122,133,366
Ensembl chr 2:122,129,381...122,133,366 		JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase, type II, gamma IAGP MGI PMID:27313209 NCBI chr10:127,032,936...127,047,508
Ensembl chr10:127,032,936...127,047,454 		JBrowse link
G Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 IEA MGI NCBI chr 9:55,985,729...56,036,174
Ensembl chr 9:55,997,246...56,036,172 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16233
    hematopoietic system phenotype 5190
      abnormal hematopoietic system morphology/development 4732
        abnormal hematopoietic cell morphology 3961
          abnormal leukocyte morphology 2645
            abnormal leukocyte cell number 2367
              abnormal lymphocyte cell number 1618
                abnormal T cell number 1033
                  abnormal effector T cell number 235
                    abnormal T-helper cell number 133
                      abnormal KLRG1-positive T-helper cell number + 6
                      abnormal T follicular helper cell number + 23
                      abnormal T-helper 1 cell number + 32
                      abnormal T-helper 17 cell number + 35
                      abnormal T-helper 2 cell number + 25
                      abnormal effector memory T-helper cell number + 38
                      decreased T-helper cell number + 43
                      increased T-helper cell number + 70
Path 2
Term Annotations click to browse term
  mammalian phenotype 16233
    immune system phenotype 5376
      abnormal immune system morphology 3802
        abnormal immune system cell morphology 2666
          abnormal leukocyte morphology 2645
            abnormal mononuclear cell morphology 2159
              abnormal lymphocyte morphology 1749
                abnormal T cell morphology 1125
                  abnormal T cell number 1033
                    abnormal effector T cell number 235
                      abnormal T-helper cell number 133
                        abnormal KLRG1-positive T-helper cell number + 6
                        abnormal T follicular helper cell number + 23
                        abnormal T-helper 1 cell number + 32
                        abnormal T-helper 17 cell number + 35
                        abnormal T-helper 2 cell number + 25
                        abnormal effector memory T-helper cell number + 38
                        decreased T-helper cell number + 43
                        increased T-helper cell number + 70
paths to the root