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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal mammary gland cord formation
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Accession:MP:0013726 term browser browse the term
Definition:any anomaly in the process by which the mammary gland cord forms by elongation of the mammary bud; in female mouse embryos, the cord is formed between E15.5 and E16.5, once the elongating bud breaks through the primary mammary mesenchyme and reaches the fat pad precursor, and remains connected to the epidermis; by E16.5 a lumen develops within the sprout resulting in a primary duct opening to the exterior, and the nipple forms by differentiation of the overlying epidermis in response to signals from specialized mammary mesenchyme; in male mouse embryos, the activation of androgen receptors causes the mammary buds to separate from the epithelium between E14.5 and E15.5 and subsequently degenerate
Synonyms:exact_synonym: abnormal mammary cord formation;   abnormal mammary sprout formation;   abnormal mammary sprouting


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Term Annotations click to browse term
  mammalian phenotype 5420
    integument phenotype 171
      abnormal skin adnexa morphology 169
        abnormal mammary gland morphology 99
          abnormal mammary gland development 7
            abnormal mammary gland cord formation 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5420
    endocrine/exocrine gland phenotype 394
      abnormal gland morphology 333
        abnormal exocrine gland morphology 119
          abnormal apocrine gland morphology 99
            abnormal mammary gland morphology 99
              abnormal mammary gland epithelium morphology 8
                abnormal mammary gland duct morphology 3
                  abnormal mammary gland cord morphology 0
                    abnormal mammary gland cord formation 0
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