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Pathways

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal granulocyte monocyte progenitor cell morphology
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Accession:MP:0013694 term browser browse the term
Definition:any structural anomaly of a hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages; these cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1
Synonyms:exact_synonym: abnormal CFU-GM morphology;   abnormal GMP morphology;   abnormal colony forming unit granulocyte macrophage morphology;   abnormal granulocyte-macrophage progenitor morphology;   abnormal granulocyte/monocyte precursor morphology;   abnormal granulocyte/monocyte progenitor morphology



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abnormal granulocyte monocyte progenitor cell morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ang angiogenin, ribonuclease, RNase A family, 5 IAGP MGI PMID:27518564 NCBI chr14:51,328,607...51,339,462
Ensembl chr14:51,328,607...51,339,466
JBrowse link
decreased granulocyte monocyte progenitor cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl7 angiopoietin-like 7 IAGP MGI PMID:25652910 NCBI chr 4:148,579,737...148,584,919
Ensembl chr 4:148,579,640...148,584,917
JBrowse link
G Bloc1s2 biogenesis of lysosomal organelles complex-1, subunit 2 IAGP MGI PMID:27719760 NCBI chr19:44,127,685...44,134,909
Ensembl chr19:44,127,685...44,134,885
JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) IAGP MGI PMID:19966810 NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724
JBrowse link
G Commd10 COMM domain containing 10 IAGP MGI PMID:22422825 NCBI chr18:47,091,917...47,242,435
Ensembl chr18:47,091,883...47,367,351
JBrowse link
G Crbn cereblon IAGP MGI PMID:30064974 NCBI chr 6:106,755,205...106,777,060
Ensembl chr 6:106,757,162...106,777,038
JBrowse link
G Dhfr dihydrofolate reductase IAGP MGI PMID:26830229 NCBI chr13:92,491,291...92,525,561
Ensembl chr13:92,491,234...92,525,561
JBrowse link
G Dhx36 DEAH-box helicase 36 IAGP MGI PMID:22422825 NCBI chr 3:62,375,436...62,414,464
Ensembl chr 3:62,375,434...62,414,425
JBrowse link
G Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 IAGP MGI PMID:22701168 NCBI chr 7:19,079,016...19,090,449
Ensembl chr 7:19,078,703...19,090,449
JBrowse link
G Fanci Fanconi anemia, complementation group I IAGP MGI PMID:31219578 NCBI chr 7:79,042,056...79,100,013
Ensembl chr 7:79,041,677...79,100,012
JBrowse link
G Ifng interferon gamma IAGP MGI PMID:25342713 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Irf8 interferon regulatory factor 8 IAGP MGI PMID:35732734 NCBI chr 8:121,463,097...121,483,433
Ensembl chr 8:121,463,097...121,483,433
JBrowse link
G Lmo2 LIM domain only 2 IAGP MGI PMID:19966810 NCBI chr 2:103,788,340...103,812,223
Ensembl chr 2:103,788,331...103,812,223
JBrowse link
G Phf6 PHD finger protein 6 IAGP MGI PMID:31395598 NCBI chr  X:52,001,091...52,045,838
Ensembl chr  X:52,001,143...52,045,820
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 IAGP MGI PMID:19179468 NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460
JBrowse link
G Sf3b1 splicing factor 3b, subunit 1 IAGP MGI PMID:27622333 NCBI chr 1:55,024,328...55,066,660
Ensembl chr 1:55,024,328...55,066,640
JBrowse link
G Smim3 small integral membrane protein 3 IAGP MGI PMID:19966810 NCBI chr18:60,607,263...60,635,055
Ensembl chr18:60,607,263...60,635,059
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:19966810 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
increased granulocyte monocyte progenitor cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Commd10 COMM domain containing 10 IAGP MGI PMID:33753942 PMID:35987460 NCBI chr18:47,091,917...47,242,435
Ensembl chr18:47,091,883...47,367,351
JBrowse link
G Fbxo21 F-box protein 21 IAGP MGI PMID:35987460 NCBI chr 5:118,114,835...118,148,263
Ensembl chr 5:118,114,795...118,148,266
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:26438359 PMID:30692594 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Kdm6a lysine (K)-specific demethylase 6A IAGP MGI PMID:29479066 NCBI chr  X:18,027,101...18,147,061
Ensembl chr  X:18,028,814...18,146,175
JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:25359213 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965
JBrowse link
G Npm1 nucleophosmin 1 IAGP MGI PMID:30692594 NCBI chr11:33,102,498...33,114,143
Ensembl chr11:33,102,287...33,113,206
JBrowse link
G Ociad1 OCIA domain containing 1 IAGP MGI PMID:30952670 NCBI chr 5:73,450,093...73,471,420
Ensembl chr 5:73,450,127...73,471,412
JBrowse link
G Pdia6 protein disulfide isomerase associated 6 IAGP MGI PMID:31985756 NCBI chr12:17,316,590...17,334,786
Ensembl chr12:17,316,546...17,334,771
JBrowse link
G Riok2 RIO kinase 2 IAGP MGI PMID:33753942 NCBI chr17:17,594,594...17,615,161
Ensembl chr17:17,594,571...17,615,161
JBrowse link
G Stag2 STAG2 cohesin complex component IAGP MGI PMID:32249213 NCBI chr  X:41,238,172...41,366,063
Ensembl chr  X:41,238,194...41,366,062
JBrowse link
G Tcim transcriptional and immune response regulator IAGP MGI PMID:24937306 NCBI chr 8:24,927,188...24,928,962
Ensembl chr 8:24,927,196...24,929,000
JBrowse link
G Trp53 transformation related protein 53 IAGP MGI PMID:29479066 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Zfand2b zinc finger, AN1 type domain 2B IAGP MGI PMID:26692333 NCBI chr 1:75,145,290...75,148,270
Ensembl chr 1:75,145,290...75,148,273
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16476
    hematopoietic system phenotype 5344
      abnormal hematopoietic system morphology/development 4885
        abnormal hematopoietic cell morphology 4062
          abnormal myeloid cell morphology 2938
            abnormal granulocyte monocyte progenitor cell morphology 29
              abnormal granulocyte monocyte progenitor cell number + 28
paths to the root