Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal adult Leydig cell differentiation
go back to main search page
Accession:MP:0013604 term browser browse the term
Definition:atypical formation of or inability to produce the second or adult population of Leydig cells (ALCs) between birth and puberty; ALCs arise in the interstitium of adult testes from unknown progenitor cells and become the major source of androgens that control differentiation of the male reproductive tract and spermatogenesis; ALCs are not derived from fetal Leydig cells (FLCs), and the origin and the molecular events that control ALC differentiation are poorly understood



show annotations for term's descendants           Sort by:
 
abnormal adult Leydig cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhh desert hedgehog signaling molecule IMP RGD PMID:21062903 RGD:38548923 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5364
    reproductive system phenotype 128
      abnormal reproductive system morphology 97
        abnormal sex gland morphology 67
          abnormal male reproductive gland morphology 58
            abnormal testis morphology 46
              abnormal testis interstitial tissue morphology 5
                abnormal Leydig cell morphology 5
                  abnormal Leydig cell differentiation 2
                    abnormal adult Leydig cell differentiation 2
Path 2
Term Annotations click to browse term
  mammalian phenotype 5364
    reproductive system phenotype 128
      abnormal reproductive system morphology 97
        abnormal male reproductive system morphology 66
          abnormal male genitalia morphology 66
            abnormal internal male genitalia morphology 58
              abnormal testis morphology 46
                abnormal testis interstitial tissue morphology 5
                  abnormal Leydig cell morphology 5
                    abnormal Leydig cell differentiation 2
                      abnormal adult Leydig cell differentiation 2
paths to the root