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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal Leydig cell differentiation
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Accession:MP:0013602 term browser browse the term
Definition:atypical formation of or inability to produce the interstitial cells that are found adjacent to the seminiferous tubules in the testicle and produce testosterone in the presence of luteinizing hormone; in most mammals, normal Leydig cell (LC) development comprises two sequential but overlapping cell lineages known as the fetal and adult type LC populations, which display distinct functional characteristics reflected by different morphology, hormonal regulation, and steroidogenic output
Synonyms:exact_synonym: abnormal LC differentiation



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abnormal adult Leydig cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhh desert hedgehog signaling molecule IMP RGD PMID:21062903 RGD:38548923 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
JBrowse link
abnormal fetal Leydig cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhh desert hedgehog signaling molecule IMP RGD PMID:21062903 RGD:38548923 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5369
    reproductive system phenotype 129
      abnormal reproductive system morphology 97
        abnormal sex gland morphology 67
          abnormal male reproductive gland morphology 58
            abnormal testis morphology 46
              abnormal testis interstitial tissue morphology 5
                abnormal Leydig cell morphology 5
                  abnormal Leydig cell differentiation 2
                    abnormal adult Leydig cell differentiation 2
                    abnormal fetal Leydig cell differentiation 2
Path 2
Term Annotations click to browse term
  mammalian phenotype 5369
    reproductive system phenotype 129
      abnormal reproductive system morphology 97
        abnormal male reproductive system morphology 66
          abnormal male genitalia morphology 66
            abnormal internal male genitalia morphology 58
              abnormal testis morphology 46
                abnormal testis interstitial tissue morphology 5
                  abnormal Leydig cell morphology 5
                    abnormal Leydig cell differentiation 2
                      abnormal adult Leydig cell differentiation 2
                      abnormal fetal Leydig cell differentiation 2
paths to the root