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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal merocrine gland physiology
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Accession:MP:0013557 term browser browse the term
Definition:any functional anomaly of any exocrine gland whose secretions are excreted via exocytosis from secretory cells into an epithelial-walled duct or ducts and thence onto a bodily surface or into the lumen; the gland releases its product and no part of the gland is lost or damaged
Synonyms:exact_synonym: abnormal eccrine gland physiology


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abnormal Harderian gland porphyrin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mc5r melanocortin 5 receptor IAGP MGI PMID:9413988 NCBI chr18:68,469,811...68,475,517
Ensembl chr18:68,470,575...68,475,517 		JBrowse link
G Prlr prolactin receptor IAGP MGI PMID:11133844 NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266 		JBrowse link
abnormal parotid gland physiology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 IAGP MGI PMID:11358967 NCBI chr 4:133,097,022...133,151,013
Ensembl chr 4:133,097,017...133,151,013 		JBrowse link
abnormal salivary gland physiology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp5 aquaporin 5 IAGP MGI PMID:10400615 PMID:11290736 NCBI chr15:99,488,909...99,492,710
Ensembl chr15:99,488,663...99,492,710 		JBrowse link
G Clcn2 chloride channel, voltage-sensitive 2 IAGP MGI PMID:11976342 NCBI chr16:20,521,185...20,536,496
Ensembl chr16:20,521,714...20,536,496 		JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 IAGP MGI PMID:19788412 NCBI chr 2:80,145,790...80,184,399
Ensembl chr 2:80,145,810...80,184,387 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:19788412 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:16413168 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Itpr2 inositol 1,4,5-triphosphate receptor 2 IAGP MGI PMID:16195467 NCBI chr 6:146,009,797...146,403,757
Ensembl chr 6:146,009,797...146,403,721 		JBrowse link
G Itpr3 inositol 1,4,5-triphosphate receptor 3 IAGP MGI PMID:16195467 NCBI chr17:27,275,976...27,341,197
Ensembl chr17:27,276,278...27,341,197 		JBrowse link
G Lrrc26 leucine rich repeat containing 26 IAGP MGI PMID:28416688 NCBI chr 2:25,179,923...25,181,205
Ensembl chr 2:25,179,927...25,181,192 		JBrowse link
G Slc5a8 solute carrier family 5 (iodide transporter), member 8 IAGP MGI PMID:18562324 NCBI chr10:88,721,854...88,765,377
Ensembl chr10:88,721,854...88,765,377 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) IAGP MGI PMID:24551030 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G Tfcp2l1 transcription factor CP2-like 1 IAGP MGI PMID:17079272 NCBI chr 1:118,555,646...118,612,898
Ensembl chr 1:118,555,675...118,612,898 		JBrowse link
abnormal submandibular gland physiology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm1 cholinergic receptor, muscarinic 1, CNS IAGP MGI PMID:15146045 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac IAGP MGI PMID:15146045 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883 		JBrowse link
G Ctnnd1 catenin delta 1 IAGP MGI PMID:16399075 NCBI chr 2:84,417,440...84,489,321
Ensembl chr 2:84,430,415...84,481,109
Ensembl chr 2:84,430,415...84,481,109 		JBrowse link
G Six1 sine oculis-related homeobox 1 IAGP MGI PMID:19371398 NCBI chr12:73,088,601...73,093,486
Ensembl chr12:73,086,789...73,100,661 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 IAGP MGI PMID:17956991 NCBI chr 9:95,587,125...95,632,438
Ensembl chr 9:95,587,135...95,632,428 		JBrowse link
decreased salivation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp5 aquaporin 5 IAGP MGI PMID:10400615 PMID:11290736 PMID:15647389 NCBI chr15:99,488,909...99,492,710
Ensembl chr15:99,488,663...99,492,710 		JBrowse link
G Aqp8 aquaporin 8 IAGP MGI PMID:15647389 NCBI chr 7:123,061,517...123,067,226
Ensembl chr 7:123,061,514...123,067,227 		JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 IAGP MGI PMID:15539463 NCBI chr 8:94,794,580...94,825,997
Ensembl chr 8:94,794,582...94,825,556 		JBrowse link
G Bbs4 Bardet-Biedl syndrome 4 IAGP MGI PMID:15539463 NCBI chr 9:59,229,249...59,260,791
Ensembl chr 9:59,229,273...59,260,791 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1, CNS IAGP MGI PMID:15146045 NCBI chr19:8,641,369...8,660,970
Ensembl chr19:8,641,153...8,660,951 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac IAGP MGI PMID:10944224 PMID:15146045 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883 		JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 IAGP MGI PMID:11900778 NCBI chr 2:112,309,078...112,365,491
Ensembl chr 2:112,309,516...112,311,114 		JBrowse link
G Commd10 COMM domain containing 10 IAGP MGI PMID:29127143 NCBI chr18:47,091,917...47,242,435
Ensembl chr18:47,091,883...47,367,351 		JBrowse link
G E2f1 E2F transcription factor 1 IAGP MGI PMID:15470032 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812 		JBrowse link
G Fgf10 fibroblast growth factor 10 IAGP MGI PMID:26321752 NCBI chr13:118,851,199...118,928,651
Ensembl chr13:118,806,327...118,928,651 		JBrowse link
G Id3 inhibitor of DNA binding 3 IAGP MGI PMID:15485632 PMID:20932862 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066 		JBrowse link
G Il17a interleukin 17A IAGP MGI PMID:25411202 NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720 		JBrowse link
G Il2ra interleukin 2 receptor, alpha chain IAGP MGI PMID:17207605 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004 		JBrowse link
G Itpr2 inositol 1,4,5-triphosphate receptor 2 IAGP MGI PMID:16195467 NCBI chr 6:146,009,797...146,403,757
Ensembl chr 6:146,009,797...146,403,721 		JBrowse link
G Itpr3 inositol 1,4,5-triphosphate receptor 3 IAGP MGI PMID:16195467 NCBI chr17:27,275,976...27,341,197
Ensembl chr17:27,276,278...27,341,197 		JBrowse link
G Nkx3-1 NK3 homeobox 1 IAGP MGI PMID:10906459 NCBI chr14:69,428,141...69,432,107
Ensembl chr14:69,428,087...69,432,111 		JBrowse link
G Oprk1 opioid receptor, kappa 1 IAGP MGI PMID:9463367 NCBI chr 1:5,658,673...5,676,357
Ensembl chr 1:5,658,689...5,676,354 		JBrowse link
G Satb1 special AT-rich sequence binding protein 1 IAGP MGI PMID:29127143 NCBI chr17:52,043,215...52,140,318
Ensembl chr17:52,043,215...52,140,318 		JBrowse link
G Slc12a2 solute carrier family 12, member 2 IAGP MGI PMID:10831596 NCBI chr18:58,011,505...58,079,893
Ensembl chr18:58,011,750...58,079,893 		JBrowse link
G Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 IAGP MGI PMID:11358967 NCBI chr 4:133,097,022...133,151,013
Ensembl chr 4:133,097,017...133,151,013 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) IAGP MGI PMID:19717635 PMID:24551030 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 IAGP MGI PMID:17956991 NCBI chr 9:95,587,125...95,632,438
Ensembl chr 9:95,587,135...95,632,428 		JBrowse link
increased salivation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grk5 G protein-coupled receptor kinase 5 IAGP MGI PMID:10624964 NCBI chr19:60,877,995...61,084,406
Ensembl chr19:60,878,187...61,084,406 		JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase IAGP MGI PMID:12734191 NCBI chr 9:50,432,917...50,440,017
Ensembl chr 9:50,432,917...50,440,024 		JBrowse link
increased submandibular gland apoptosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnnd1 catenin delta 1 IAGP MGI PMID:16399075 NCBI chr 2:84,417,440...84,489,321
Ensembl chr 2:84,430,415...84,481,109
Ensembl chr 2:84,430,415...84,481,109 		JBrowse link
parotid gland inflammation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator IAGP MGI PMID:15699112 PMID:19265170 NCBI chr10:77,865,856...77,879,444
Ensembl chr10:77,865,856...77,879,444 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 IAGP MGI PMID:16473829 NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903 		JBrowse link
G Id3 inhibitor of DNA binding 3 IAGP MGI PMID:20932862 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066 		JBrowse link
G Il12rb2 interleukin 12 receptor, beta 2 IAGP MGI PMID:16081683 NCBI chr 6:67,263,914...67,353,277
Ensembl chr 6:67,268,302...67,353,172 		JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 IAGP MGI PMID:18624351 NCBI chr10:39,488,930...39,531,303
Ensembl chr10:39,488,930...39,531,303 		JBrowse link
salivary gland inflammation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator IAGP MGI PMID:15699112 PMID:16172259 PMID:18414681 NCBI chr10:77,865,856...77,879,444
Ensembl chr10:77,865,856...77,879,444 		JBrowse link
G Ccnt1 cyclin T1 IAGP MGI PMID:17938200 NCBI chr15:98,436,570...98,468,340
Ensembl chr15:98,436,570...98,468,804 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 IAGP MGI PMID:16473829 NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903 		JBrowse link
G Clec4a2 C-type lectin domain family 4, member a2 IAGP MGI PMID:18204462 NCBI chr 6:123,099,627...123,119,891
Ensembl chr 6:123,083,387...123,120,958 		JBrowse link
G Commd10 COMM domain containing 10 IAGP MGI PMID:29127143 NCBI chr18:47,091,917...47,242,435
Ensembl chr18:47,091,883...47,367,351 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 IAGP MGI PMID:7584144 PMID:18845758 NCBI chr 1:60,948,184...60,954,991
Ensembl chr 1:60,926,159...60,954,991 		JBrowse link
G Ctsb cathepsin B IAGP MGI PMID:19664906 NCBI chr14:63,359,911...63,383,372
Ensembl chr14:63,359,911...63,383,372 		JBrowse link
G Ctsl cathepsin L IAGP MGI PMID:19664906 NCBI chr13:64,509,704...64,518,586
Ensembl chr13:64,507,151...64,518,704 		JBrowse link
G Ctss cathepsin S IAGP MGI PMID:19664906 NCBI chr 3:95,434,097...95,463,716
Ensembl chr 3:95,434,097...95,463,714 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IAGP MGI PMID:15314222 PMID:25447050 NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394 		JBrowse link
G E2f1 E2F transcription factor 1 IAGP MGI PMID:15470032 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812 		JBrowse link
G Fas Fas cell surface death receptor IAGP MGI PMID:1565490 PMID:8163351 PMID:15265950 PMID:16339515 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Fcgr2b Fc receptor, IgG, low affinity IIb IAGP MGI PMID:10981970 NCBI chr 1:170,786,186...170,804,141
Ensembl chr 1:170,786,186...170,804,116 		JBrowse link
G Foxo3 forkhead box O3 IAGP MGI PMID:15308101 NCBI chr10:42,057,841...42,152,691
Ensembl chr10:42,057,837...42,152,751 		JBrowse link
G Foxp3 forkhead box P3 IAGP MGI PMID:17207605 PMID:18845758 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 IAGP MGI PMID:10620608 PMID:11285306 PMID:14570980 PMID:14764740 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393 		JBrowse link
G Id3 inhibitor of DNA binding 3 IAGP MGI PMID:15485632 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066 		JBrowse link
G Ifnar1 interferon (alpha and beta) receptor 1 IAGP MGI PMID:15265950 NCBI chr16:91,281,016...91,307,411
Ensembl chr16:91,282,126...91,304,329 		JBrowse link
G Ifngr1 interferon gamma receptor 1 IAGP MGI PMID:15265950 NCBI chr10:19,467,697...19,485,977
Ensembl chr10:19,467,697...19,485,977 		JBrowse link
G Il12rb2 interleukin 12 receptor, beta 2 IAGP MGI PMID:16081683 NCBI chr 6:67,263,914...67,353,277
Ensembl chr 6:67,268,302...67,353,172 		JBrowse link
G Il2ra interleukin 2 receptor, alpha chain IAGP MGI PMID:17207605 NCBI chr 2:11,647,603...11,698,005
Ensembl chr 2:11,647,618...11,698,004 		JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:16413168 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Ins1 insulin I IAGP MGI PMID:15889095 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914 		JBrowse link
G Ins2 insulin II IAGP MGI PMID:15889095 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Lat linker for activation of T cells IAGP MGI PMID:29902238 NCBI chr 7:125,962,999...125,968,877
Ensembl chr 7:125,962,996...125,968,742 		JBrowse link
G Mark2 MAP/microtubule affinity regulating kinase 2 IAGP MGI PMID:11287624 NCBI chr19:7,252,761...7,319,222
Ensembl chr19:7,252,761...7,319,225 		JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IAGP MGI PMID:34420035 NCBI chr18:70,701,298...70,761,769
Ensembl chr18:70,701,260...70,759,202 		JBrowse link
G Mtus1 mitochondrial tumor suppressor 1 IAGP MGI PMID:22200760 NCBI chr 8:41,443,949...41,587,318
Ensembl chr 8:41,443,951...41,586,763 		JBrowse link
G Pip4k2c phosphatidylinositol-5-phosphate 4-kinase, type II, gamma IAGP MGI PMID:27313209 NCBI chr10:127,032,936...127,047,508
Ensembl chr10:127,032,936...127,047,454 		JBrowse link
G Polb polymerase (DNA directed), beta IAGP MGI PMID:24388753 NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IAGP MGI PMID:7957574 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 IAGP MGI PMID:18806225 NCBI chr 6:124,697,670...124,715,672
Ensembl chr 6:124,697,670...124,715,677 		JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B IAGP MGI PMID:7834753 NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363 		JBrowse link
G Satb1 special AT-rich sequence binding protein 1 IAGP MGI PMID:29127143 NCBI chr17:52,043,215...52,140,318
Ensembl chr17:52,043,215...52,140,318 		JBrowse link
G Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 IAGP MGI PMID:24828632 NCBI chr 3:63,849,744...63,872,154
Ensembl chr 3:63,840,928...63,872,189 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 IAGP MGI PMID:11606785 NCBI chr16:10,601,672...10,603,400
Ensembl chr16:10,600,104...10,603,400 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IAGP MGI PMID:1436033 PMID:8421714 PMID:19415629 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tlr7 toll-like receptor 7 IAGP MGI PMID:35477763 NCBI chr  X:166,086,376...166,113,570
Ensembl chr  X:166,087,925...166,113,554 		JBrowse link
G Trex1 three prime repair exonuclease 1 IAGP MGI PMID:25848017 NCBI chr 9:108,887,000...108,888,791
Ensembl chr 9:108,887,001...108,888,802 		JBrowse link
G Xcl1 chemokine (C motif) ligand 1 IAGP MGI PMID:21300913 NCBI chr 1:164,759,216...164,763,094
Ensembl chr 1:164,759,213...164,763,096 		JBrowse link
sublingual gland inflammation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator IAGP MGI PMID:19265170 NCBI chr10:77,865,856...77,879,444
Ensembl chr10:77,865,856...77,879,444 		JBrowse link
submandibular gland inflammation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator IAGP MGI PMID:15699112 NCBI chr10:77,865,856...77,879,444
Ensembl chr10:77,865,856...77,879,444 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 IAGP MGI PMID:16473829 NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903 		JBrowse link
G Fas Fas cell surface death receptor IAGP MGI PMID:7957574 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172 		JBrowse link
G Id3 inhibitor of DNA binding 3 IAGP MGI PMID:20932862 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066 		JBrowse link
G Il12rb2 interleukin 12 receptor, beta 2 IAGP MGI PMID:16081683 NCBI chr 6:67,263,914...67,353,277
Ensembl chr 6:67,268,302...67,353,172 		JBrowse link
G St14 suppression of tumorigenicity 14 (colon carcinoma) IAGP MGI PMID:24551030 NCBI chr 9:30,999,886...31,043,138
Ensembl chr 9:31,000,698...31,043,149 		JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 IAGP MGI PMID:18624351 NCBI chr10:39,488,930...39,531,303
Ensembl chr10:39,488,930...39,531,303 		JBrowse link
xerostomia term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf10 fibroblast growth factor 10 IAGP MGI PMID:26321752 NCBI chr13:118,851,199...118,928,651
Ensembl chr13:118,806,327...118,928,651 		JBrowse link
G Traf3ip2 TRAF3 interacting protein 2 IAGP MGI PMID:18624351 NCBI chr10:39,488,930...39,531,303
Ensembl chr10:39,488,930...39,531,303 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16476
    endocrine/exocrine gland phenotype 3362
      abnormal gland physiology 903
        abnormal exocrine gland physiology 260
          abnormal merocrine gland physiology 80
            abnormal Harderian gland physiology + 2
            abnormal salivary gland physiology + 78
paths to the root