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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal Meibomian gland physiology
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Accession:MP:0013391 term browser browse the term
Definition:any functional anomaly of the meibum-secreting modified lobulated sebaceous glands located at the rim of the eyelids inside the tarsal plate; dysfunctional Meibomian glands may produce an excessive amount of oil, cause dry eyes, or contribute to blepharitis
Synonyms:exact_synonym: Meibomian gland dysfunction


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abnormal Meibomian gland physiology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Awat1 acyl-CoA wax alcohol acyltransferase 1 IAGP MGI PMID:34113821 NCBI chr  X:99,615,853...99,621,812
Ensembl chr  X:99,615,857...99,621,811 		JBrowse link
G Awat2 acyl-CoA wax alcohol acyltransferase 2 IAGP MGI PMID:32851726 PMID:34113821 NCBI chr  X:99,445,827...99,537,885
Ensembl chr  X:99,445,827...99,486,323 		JBrowse link
G Cyp4f39 cytochrome P450, family 4, subfamily f, polypeptide 39 IAGP MGI PMID:34113821 NCBI chr17:32,671,670...32,712,294
Ensembl chr17:32,671,697...32,712,294 		JBrowse link
G Far2 fatty acyl CoA reductase 2 IAGP MGI PMID:35238077 NCBI chr 6:147,948,914...148,084,256
Ensembl chr 6:147,948,757...148,084,256 		JBrowse link
G Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 IAGP MGI PMID:37117756 NCBI chr 3:98,712,820...98,721,759
Ensembl chr 3:98,712,820...98,721,759 		JBrowse link
G Klf5 Kruppel-like transcription factor 5 IAGP MGI PMID:21600198 NCBI chr14:99,536,127...99,550,848
Ensembl chr14:99,536,127...99,552,472 		JBrowse link
G Sod1 superoxide dismutase 1, soluble IAGP MGI PMID:25036096 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
Meibomian gland inflammation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hr lysine demethylase and nuclear receptor corepressor IAGP MGI PMID:24845637 NCBI chr14:70,789,644...70,810,988
Ensembl chr14:70,789,652...70,810,988 		JBrowse link
G Sod1 superoxide dismutase 1, soluble IAGP MGI PMID:25036096 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16954
    integument phenotype 2836
      abnormal skin adnexa physiology 244
        abnormal sebaceous gland physiology 25
          abnormal Meibomian gland physiology 8
            Meibomian gland inflammation 2
Path 2
Term Annotations click to browse term
  mammalian phenotype 16954
    endocrine/exocrine gland phenotype 3449
      abnormal gland physiology 923
        abnormal exocrine gland physiology 265
          abnormal holocrine gland physiology 25
            abnormal sebaceous gland physiology 25
              abnormal Meibomian gland physiology 8
                Meibomian gland inflammation 2
paths to the root