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Pathways

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal sebocyte differentiation
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Accession:MP:0013376 term browser browse the term
Definition:abnormal formation or arrest of differentiation of the sebum-producing epithelial cells of the sebaceous glands that release their content by rupture of the cell membrane and cellular degradation; these cells are most commonly found in the skin in association with hair follicles (forming the pilosebaceous unit), where they arise from hair follicle keratinocytes, but there are also sebaceous glands not associated with a hair follicle; the latter have special functions as secretion of pheromones or corneal protection; sebocyte differentiation is defined by increasing accumulation of lipid droplets, the major component of sebum
Synonyms:exact_synonym: abnormal acinar cell of sebaceous gland differentiation;   abnormal sebaceous epithelial cell differentiation



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Path 1
Term Annotations click to browse term
  mammalian phenotype 5380
    integument phenotype 168
      abnormal skin adnexa morphology 166
        abnormal skin adnexa development 7
          abnormal sebocyte differentiation 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5380
    endocrine/exocrine gland phenotype 391
      abnormal gland morphology 330
        abnormal exocrine gland morphology 116
          abnormal holocrine gland morphology 3
            abnormal sebaceous gland morphology 3
              abnormal sebocyte morphology 0
                abnormal sebocyte differentiation 0
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