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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal folliculo-stellate cell morphology
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Accession:MP:0013341 term browser browse the term
Definition:any structural anomaly of the star-shaped and follicle-forming cells in the anterior pituitary gland that stain positive for S-100 protein (a marker for FS-cells); ascribed functions include the formation of an extensive and complex tridimentional network, scavenger activity by engulfing degenerated cells, paracrine regulation of endocrine cells by producing various growth factors and cytokines, such as interleukin-6, leukemia inhibitory factor, basic fibroblastic growth factor, vascular endothelial cell growth factor and follistatin, and large-scale inter-cellular communication by means of their long cytoplasmic processes and gap junctions
Synonyms:exact_synonym: abnormal FS-cell morphology;   abnormal FS-cells;   abnormal folliculostellate cell morphology



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Path 1
Term Annotations click to browse term
  mammalian phenotype 5364
    endocrine/exocrine gland phenotype 390
      abnormal gland morphology 330
        abnormal endocrine gland morphology 143
          abnormal neuroendocrine gland morphology 42
            abnormal pituitary gland morphology 42
              abnormal adenohypophysis morphology 10
                abnormal folliculo-stellate cell morphology 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5364
    nervous system phenotype 360
      abnormal nervous system morphology 208
        abnormal brain morphology 136
          abnormal forebrain morphology 79
            abnormal diencephalon morphology 45
              abnormal pituitary gland morphology 42
                abnormal adenohypophysis morphology 10
                  abnormal folliculo-stellate cell morphology 0
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