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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal adenohypophysis development
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Accession:MP:0013337 term browser browse the term
Definition:aberrant formation or incomplete differentiation of the anterior lobe of the pituitary gland which arises as a pouch-like outgrowth of ectoderm known as the hypophyseal (Rathke's) pouch from the dorsal midline roof of the stomodeum (primitive oral cavity); the hypophyseal pouch grows toward the brain and the neurohypophyseal bud; as the hypophyseal pouch and the infundibulum make contact, the hypophyseal pouch loses its connection with the pharynx, creating a hollow ball of cells that lies inferior to the floor of the diencephalon posterior to the optic chiasm; these cells undergo division, the central chamber gradually disappears, and this endocrine mass becomes the anterior pituitary gland; the fully developed adenohypophysis consists of a glandular pars distalis, a thin proximal extension called the pars tuberalis, and a narrow pars intermedia
Synonyms:exact_synonym: abnormal adenophysis development;   abnormal anterior pituitary development;   abnormal anterior pituitary gland development;   abnormal anterior pituitary lobe development



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Path 1
Term Annotations click to browse term
  mammalian phenotype 5364
    endocrine/exocrine gland phenotype 390
      abnormal gland morphology 330
        abnormal gland development 7
          abnormal pituitary gland development 0
            abnormal adenohypophysis development 0
              abnormal pituitary diverticulum morphology + 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5364
    nervous system phenotype 360
      abnormal nervous system morphology 208
        abnormal brain morphology 136
          abnormal forebrain morphology 79
            abnormal diencephalon morphology 45
              abnormal pituitary gland morphology 42
                abnormal pituitary gland development 0
                  abnormal adenohypophysis development 0
                    abnormal pituitary diverticulum morphology + 0
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