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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

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Accession:MP:0013305 term browser browse the term
Definition:inability of the kidneys to produce either a concentrated or a dilute urine; refers to a state in chronic renal disease in which the kidney cannot form urine with a higher or a lower specific gravity (concentration) than that of protein-free plasma; the specific gravity of the urine becomes fixed, irrespective of the fluid intake
Synonyms:exact_synonym: impaired urine-concentrating ability;   urine concentrating defect

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isosthenuria term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 treatment IAGP RGD PMID:1127102 RGD:1354700 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a1j UDP glucuronosyltransferase family 1 member A1, jaundice mutant treatment IAGP RGD PMID:1127102 RGD:1354700

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  mammalian phenotype 5402
    renal/urinary system phenotype 649
      abnormal renal/urinary system physiology 478
        abnormal kidney physiology 142
          isosthenuria 3
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