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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal cardiac neural crest cell morphology
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Accession:MP:0012747 term browser browse the term
Definition:any structural anomaly of the cardiac neural crest cells (NCCs), a subpopulation of cranial NCCs originating from the lower hindbrain between the otic placode and third somite; cardiac NCCs migrate to the circumpharyngeal ridge (an arc-shape ridge located dorsal to the forming caudal pharyngeal arches) and then into the 3rd, 4th and 6th pharyngeal arches and the cardiac outflow tract (OFT); cardiac NCCs contribute to the remodeling of arch arteries, septation of the cardiac OFT, closure of the ventricular septum, and innervation of the cardiac ganglia
Synonyms:exact_synonym: abnormal cardiac NCC morphology


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Path 1
Term Annotations click to browse term
  mammalian phenotype 5420
    cardiovascular system phenotype 1371
      abnormal cardiovascular system morphology 427
        abnormal cardiovascular development 12
          abnormal cardiac neural crest cell morphology 0
            decreased cardiac neural crest cell number + 0
            impaired cardiac neural crest cell differentiation 0
            increased cardiac neural crest cell number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5420
    embryo phenotype 12
      abnormal embryo morphology 2
        abnormal embryonic tissue morphology 1
          abnormal pluripotent precursor cell morphology 0
            abnormal multipotent stem cell morphology 0
              abnormal neural crest cell morphology 0
                abnormal cardiac neural crest cell morphology 0
                  decreased cardiac neural crest cell number + 0
                  impaired cardiac neural crest cell differentiation 0
                  increased cardiac neural crest cell number 0
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