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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal Brunner's gland morphology
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Accession:MP:0012518 term browser browse the term
Definition:any structural anomaly of the branched acinotubular glands found in the submucosa of the duodenum located above the Sphincter of Oddi; their main function is to produce a mucus-rich alkaline secretion (containing bicarbonate) to protect the duodenum from the acidic content of chyme, provide an alkaline condition for the intestinal enzymes to be active (thus enabling absorption to take place), and lubricate the intestinal walls; they also secrete urogastrone, which inhibits parietal and chief cells of the stomach from secreting acid and their digestive enzymes
Synonyms:exact_synonym: abnormal duodenal gland morphology;   abnormal gland of Brunner morphology;   abnormal glandula duodenales Brunneri morphology;   abnormal glandula duodenales morphology



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abnormal Brunner's gland morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr cystic fibrosis transmembrane conductance regulator IAGP MGI PMID:1380723 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link
absent Brunner's glands term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdx1 pancreatic and duodenal homeobox 1 IAGP MGI PMID:8631275 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658
JBrowse link
dilated Brunner's gland term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cftr cystic fibrosis transmembrane conductance regulator IAGP MGI PMID:7560099 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16968
    digestive/alimentary phenotype 1916
      abnormal digestive system morphology 1572
        abnormal intestine morphology 687
          abnormal small intestine morphology 276
            abnormal Brunner's gland morphology 2
              Brunner’s gland hyperplasia 0
              absent Brunner's glands 1
              dilated Brunner's gland 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 16968
    endocrine/exocrine gland phenotype 3453
      abnormal gland morphology 3212
        abnormal exocrine gland morphology 1112
          abnormal mucous gland morphology 52
            abnormal submucosal gland morphology 5
              abnormal Brunner's gland morphology 2
                Brunner’s gland hyperplasia 0
                absent Brunner's glands 1
                dilated Brunner's gland 1
paths to the root