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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:brain atrophy
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Accession:MP:0012506 term browser browse the term
Definition:acquired diminution of the size of the brain associated with wasting as from death and reabsorption of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes
Synonyms:exact_synonym: atrophic brain
 related_synonym: Global brain atrophy
 xref: HP:0002283


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Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S SD-Nme7em1Pdra-/- IMP compared to wild type SD littermate RGD PMID:33916973 RGD:407420260
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  mammalian phenotype 5440
    nervous system phenotype 386
      abnormal nervous system morphology 222
        abnormal brain morphology 142
          brain atrophy 1
            forebrain atrophy + 0
            hindbrain atrophy + 0
            midbrain atrophy 0
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