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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal basophil cell number
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Accession:MP:0012442 term browser browse the term
Definition:deviation of the count of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size


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decreased basophil cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ablim3 actin binding LIM protein family, member 3 IEA MGI NCBI chr18:61,932,463...62,044,956
Ensembl chr18:61,932,463...62,044,895 		JBrowse link
G Blnk B cell linker IEA MGI NCBI chr19:40,917,371...40,982,664
Ensembl chr19:40,917,371...40,982,978 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 IAGP MGI PMID:21799179 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A IAGP MGI PMID:11970874 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Chmp4c charged multivesicular body protein 4C IEA MGI NCBI chr 3:10,432,033...10,456,065
Ensembl chr 3:10,431,967...10,493,916 		JBrowse link
G Col4a3 collagen, type IV, alpha 3 IEA MGI NCBI chr 1:82,564,647...82,699,778
Ensembl chr 1:82,564,642...82,699,780 		JBrowse link
G Cpa3 carboxypeptidase A3, mast cell IAGP MGI PMID:22101159 NCBI chr 3:20,269,780...20,296,373
Ensembl chr 3:20,269,784...20,296,345 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha IAGP MGI PMID:11970874 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441 		JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 IAGP MGI PMID:17923703 NCBI chr18:24,338,401...24,419,873
Ensembl chr18:24,338,401...24,419,875 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble IEA MGI NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044 		JBrowse link
G Il21r interleukin 21 receptor IAGP MGI PMID:17077330 NCBI chr 7:125,202,424...125,232,742
Ensembl chr 7:125,202,601...125,232,742 		JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:22326582 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Kiss1r KISS1 receptor IAGP MGI PMID:22067321 NCBI chr10:79,752,786...79,759,922
Ensembl chr10:79,752,805...79,758,107 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:22101159 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 IAGP MGI PMID:22001390 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487 		JBrowse link
G Mcpt8 mast cell protease 8 IAGP MGI PMID:20664169 NCBI chr14:56,319,620...56,322,951
Ensembl chr14:56,319,623...56,322,730 		JBrowse link
G Pard3 par-3 family cell polarity regulator IEA MGI NCBI chr 8:127,790,131...128,338,767
Ensembl chr 8:127,790,643...128,338,767 		JBrowse link
G Pcdhb13 protocadherin beta 13 IEA MGI NCBI chr18:37,575,570...37,579,262
Ensembl chr18:37,575,553...37,579,262 		JBrowse link
G Tbk1 TANK-binding kinase 1 IAGP MGI PMID:20651301 NCBI chr10:121,382,360...121,422,699
Ensembl chr10:121,382,360...121,422,692 		JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B IEA MGI NCBI chr11:51,875,965...51,894,972
Ensembl chr11:51,876,324...51,891,589 		JBrowse link
increased basophil cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars2 alanyl-tRNA synthetase 2, mitochondrial IEA MGI NCBI chr17:45,817,473...45,831,769
Ensembl chr17:45,817,767...45,831,769 		JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 IEA MGI NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231 		JBrowse link
G Abhd10 abhydrolase domain containing 10 IEA MGI NCBI chr16:45,550,088...45,563,355
Ensembl chr16:45,550,088...45,563,318 		JBrowse link
G Acsm1 acyl-CoA synthetase medium-chain family member 1 IEA MGI NCBI chr 7:119,216,980...119,261,738
Ensembl chr 7:119,206,249...119,261,738 		JBrowse link
G Ahcy S-adenosylhomocysteine hydrolase IEA MGI NCBI chr 2:154,901,230...154,916,417
Ensembl chr 2:154,901,230...154,916,417 		JBrowse link
G Alg1 ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase IEA MGI NCBI chr16:5,051,410...5,062,773
Ensembl chr16:5,051,485...5,062,776 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase IAGP MGI PMID:17043146 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857 		JBrowse link
G Art1 ADP-ribosyltransferase 1 IEA MGI NCBI chr 7:101,750,913...101,771,410
Ensembl chr 7:101,750,950...101,763,140 		JBrowse link
G Ash1l ASH1 like histone lysine methyltransferase IEA MGI NCBI chr 3:88,857,721...88,986,682
Ensembl chr 3:88,857,929...88,986,682 		JBrowse link
G Baz1a bromodomain adjacent to zinc finger domain 1A IEA MGI NCBI chr12:54,939,774...55,061,155
Ensembl chr12:54,939,774...55,061,133 		JBrowse link
G Bcar3 breast cancer anti-estrogen resistance 3 IEA MGI NCBI chr 3:122,213,406...122,323,840
Ensembl chr 3:122,087,785...122,323,840 		JBrowse link
G Boc BOC cell adhesion associated, oncogene regulated IEA MGI NCBI chr16:44,305,408...44,379,233
Ensembl chr16:44,305,412...44,379,260 		JBrowse link
G Bod1 biorientation of chromosomes in cell division 1 IEA MGI NCBI chr11:31,615,150...31,621,862
Ensembl chr11:31,615,181...31,621,885 		JBrowse link
G Bok BCL2-related ovarian killer IEA MGI NCBI chr 1:93,613,297...93,623,492
Ensembl chr 1:93,613,382...93,623,486 		JBrowse link
G Cd1d1 CD1d1 antigen IEA MGI NCBI chr 3:86,903,141...86,919,665
Ensembl chr 3:86,903,141...86,906,748 		JBrowse link
G Cdc42ep5 CDC42 effector protein 5 IEA MGI NCBI chr 7:4,154,259...4,167,830
Ensembl chr 7:4,154,259...4,167,859 		JBrowse link
G Cib2 calcium and integrin binding family member 2 IEA MGI NCBI chr 9:54,452,074...54,467,512
Ensembl chr 9:54,452,078...54,467,502 		JBrowse link
G Clcnkb chloride channel, voltage-sensitive Kb IEA MGI NCBI chr 4:141,131,668...141,143,440
Ensembl chr 4:141,131,664...141,143,325 		JBrowse link
G Cldn9 claudin 9 IEA MGI NCBI chr17:23,901,558...23,903,000
Ensembl chr17:23,901,558...23,903,000 		JBrowse link
G Clstn1 calsyntenin 1 IEA MGI NCBI chr 4:149,670,536...149,733,356
Ensembl chr 4:149,670,925...149,733,356 		JBrowse link
G Col17a1 collagen, type XVII, alpha 1 IAGP MGI PMID:25310407 NCBI chr19:47,634,783...47,680,460
Ensembl chr19:47,634,783...47,680,533 		JBrowse link
G Ctu2 cytosolic thiouridylase subunit 2 IEA MGI NCBI chr 8:123,202,882...123,209,831
Ensembl chr 8:123,202,882...123,210,877 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 IEA MGI NCBI chr 5:96,104,785...96,108,927
Ensembl chr 5:96,104,810...96,108,927 		JBrowse link
G Eddm3b epididymal protein 3B IEA MGI NCBI chr14:51,351,886...51,355,248
Ensembl chr14:51,351,883...51,355,264 		JBrowse link
G Emc4 ER membrane protein complex subunit 4 IEA MGI NCBI chr 2:112,193,349...112,209,532
Ensembl chr 2:112,193,356...112,198,372 		JBrowse link
G Enpp3 ectonucleotide pyrophosphatase/phosphodiesterase 3 IAGP MGI PMID:25692702 NCBI chr10:24,649,712...24,712,093
Ensembl chr10:24,648,304...24,718,721 		JBrowse link
G Epg5 ectopic P-granules 5 autophagy tethering factor IEA MGI NCBI chr18:77,981,618...78,080,539
Ensembl chr18:77,981,680...78,078,228 		JBrowse link
G Fancl Fanconi anemia, complementation group L IEA MGI NCBI chr11:26,337,084...26,421,883
Ensembl chr11:26,336,135...26,421,876 		JBrowse link
G Fbxl18 F-box and leucine-rich repeat protein 18 IEA MGI NCBI chr 5:142,852,701...142,882,696
Ensembl chr 5:142,852,701...142,881,176 		JBrowse link
G Fbxl19 F-box and leucine-rich repeat protein 19 IEA MGI NCBI chr 7:127,343,059...127,368,655
Ensembl chr 7:127,343,715...127,368,655 		JBrowse link
G Fbxo28 F-box protein 28 IEA MGI NCBI chr 1:182,140,667...182,169,171
Ensembl chr 1:182,140,667...182,169,194 		JBrowse link
G Fbxo36 F-box protein 36 IEA MGI NCBI chr 1:84,817,562...84,878,208
Ensembl chr 1:84,817,562...84,878,208 		JBrowse link
G Fbxo9 f-box protein 9 IEA MGI NCBI chr 9:77,988,781...78,016,347
Ensembl chr 9:77,988,781...78,016,347 		JBrowse link
G Fbxw2 F-box and WD-40 domain protein 2 IEA MGI NCBI chr 2:34,694,185...34,716,229
Ensembl chr 2:34,694,526...34,716,323 		JBrowse link
G Fbxw8 F-box and WD-40 domain protein 8 IEA MGI NCBI chr 5:118,203,046...118,293,523
Ensembl chr 5:118,203,030...118,293,529 		JBrowse link
G Gp9 glycoprotein 9 platelet IEA MGI NCBI chr 6:87,753,115...87,756,768
Ensembl chr 6:87,755,054...87,756,750 		JBrowse link
G Gprc5c G protein-coupled receptor, family C, group 5, member C IAGP MGI PMID:21840300 NCBI chr11:114,741,976...114,763,443
Ensembl chr11:114,741,978...114,763,443 		JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:26304963 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294 		JBrowse link
G Has1 hyaluronan synthase 1 IEA MGI NCBI chr17:18,063,588...18,075,450
Ensembl chr17:18,063,585...18,075,467 		JBrowse link
G Hddc2 HD domain containing 2 IEA MGI NCBI chr10:31,189,296...31,204,200
Ensembl chr10:31,189,379...31,204,200 		JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 IEA MGI NCBI chr12:51,790,504...51,876,540
Ensembl chr12:51,790,505...51,876,319 		JBrowse link
G Herc4 hect domain and RLD 4 IEA MGI NCBI chr10:63,079,122...63,153,660
Ensembl chr10:63,079,589...63,153,657 		JBrowse link
G Herc6 hect domain and RLD 6 IEA MGI NCBI chr 6:57,557,977...57,642,121
Ensembl chr 6:57,557,985...57,641,617 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D IEA MGI NCBI chr 5:100,103,794...100,126,926
Ensembl chr 5:100,103,794...100,126,797 		JBrowse link
G Hook3 hook microtubule tethering protein 3 IEA MGI NCBI chr 8:26,511,449...26,609,646
Ensembl chr 8:26,511,449...26,609,252 		JBrowse link
G Igh-7 immunoglobulin heavy chain 7 (heavy chain of IgE) IAGP MGI PMID:20512127
G Ikzf1 IKAROS family zinc finger 1 IAGP MGI PMID:7923373 NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926 		JBrowse link
G Il4 interleukin 4 IAGP MGI PMID:20512127 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Itgb2 integrin beta 2 IAGP MGI PMID:8700894 NCBI chr10:77,366,164...77,401,542
Ensembl chr10:77,366,086...77,401,542 		JBrowse link
G Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 IEA MGI NCBI chr 1:172,148,075...172,156,889
Ensembl chr 1:172,148,068...172,156,885 		JBrowse link
G Kcnk13 potassium channel, subfamily K, member 13 IEA MGI NCBI chr12:99,928,132...100,028,941
Ensembl chr12:99,930,758...100,028,941 		JBrowse link
G Kdm1a lysine (K)-specific demethylase 1A IEA MGI NCBI chr 4:136,277,844...136,330,127
Ensembl chr 4:136,277,851...136,330,034 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase IAGP MGI PMID:20512127 NCBI chr 5:75,735,647...75,817,382
Ensembl chr 5:75,735,576...75,817,382 		JBrowse link
G Klk4 kallikrein related-peptidase 4 (prostase, enamel matrix, prostate) IEA MGI NCBI chr 7:43,530,584...43,535,228
Ensembl chr 7:43,530,584...43,535,228 		JBrowse link
G Kras Kirsten rat sarcoma viral oncogene homolog IAGP MGI PMID:25359213 NCBI chr 6:145,162,425...145,197,631
Ensembl chr 6:145,162,425...145,195,965 		JBrowse link
G Lama4 laminin, alpha 4 IEA MGI NCBI chr10:38,841,511...38,986,184
Ensembl chr10:38,841,511...38,986,184 		JBrowse link
G Ldb3 LIM domain binding 3 IEA MGI NCBI chr14:34,248,656...34,312,276
Ensembl chr14:34,248,560...34,310,639 		JBrowse link
G Limd1 LIM domains containing 1 IEA MGI NCBI chr 9:123,306,790...123,350,617
Ensembl chr 9:123,307,771...123,350,617 		JBrowse link
G Lpin3 lipin 3 IEA MGI NCBI chr 2:160,722,590...160,747,920
Ensembl chr 2:160,722,590...160,747,922 		JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor IEA MGI NCBI chr 7:34,043,569...34,089,134
Ensembl chr 7:34,044,071...34,092,740 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IAGP MGI PMID:20512127 NCBI chr 4:3,676,865...3,791,612
Ensembl chr 4:3,678,115...3,813,122 		JBrowse link
G Mmgt2 membrane magnesium transporter 2 IEA MGI NCBI chr11:62,538,999...62,557,185
Ensembl chr11:62,539,490...62,557,180 		JBrowse link
G Nexmif neurite extension and migration factor IEA MGI NCBI chr  X:103,120,367...103,245,403
Ensembl chr  X:103,121,040...103,244,791 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 IEA MGI NCBI chr11:115,054,138...115,072,009
Ensembl chr11:115,054,167...115,072,007 		JBrowse link
G Nkg7 natural killer cell group 7 sequence IEA MGI NCBI chr 7:43,086,562...43,087,670
Ensembl chr 7:43,086,497...43,087,673 		JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell IEA MGI NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472 		JBrowse link
G Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 IEA MGI NCBI chr 3:87,685,551...87,702,549
Ensembl chr 3:87,685,551...87,702,469 		JBrowse link
G Otud6a OTU domain containing 6A IEA MGI NCBI chr  X:99,472,514...99,474,859
Ensembl chr  X:99,472,619...99,473,491 		JBrowse link
G Otud6b OTU domain containing 6B IEA MGI NCBI chr 4:14,809,503...14,826,413
Ensembl chr 4:14,809,498...14,826,587 		JBrowse link
G P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 IAGP MGI PMID:25692702 NCBI chr 5:122,781,990...122,830,399
Ensembl chr 5:122,781,974...122,829,495 		JBrowse link
G Parp12 poly (ADP-ribose) polymerase family, member 12 IEA MGI NCBI chr 6:39,063,346...39,095,283
Ensembl chr 6:39,063,344...39,095,283 		JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 IEA MGI NCBI chr 1:130,616,780...130,656,990
Ensembl chr 1:130,616,919...130,656,990
Ensembl chr 1:130,616,919...130,656,990 		JBrowse link
G Phldb2 pleckstrin homology like domain, family B, member 2 IEA MGI NCBI chr16:45,566,593...45,773,961
Ensembl chr16:45,566,606...45,773,961 		JBrowse link
G Ramp1 receptor (calcitonin) activity modifying protein 1 IEA MGI NCBI chr 1:91,107,544...91,152,918
Ensembl chr 1:91,107,544...91,152,918 		JBrowse link
G Rft1 RFT1 homolog IEA MGI NCBI chr14:30,375,041...30,413,274
Ensembl chr14:30,376,317...30,413,274 		JBrowse link
G Ric8b RIC8 guanine nucleotide exchange factor B IEA MGI NCBI chr10:84,753,136...84,854,201
Ensembl chr10:84,753,480...84,854,201 		JBrowse link
G Sbno1 strawberry notch 1 IEA MGI NCBI chr 5:124,506,765...124,564,059
Ensembl chr 5:124,506,765...124,564,064 		JBrowse link
G Sirt1 sirtuin 1 IEA MGI NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 IEA MGI NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433 		JBrowse link
G Smoc1 SPARC related modular calcium binding 1 IEA MGI NCBI chr12:81,073,582...81,233,188
Ensembl chr12:81,073,582...81,233,188 		JBrowse link
G Speg SPEG complex locus IEA MGI NCBI chr 1:75,351,931...75,408,964
Ensembl chr 1:75,351,941...75,408,964 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IEA MGI NCBI chr 1:52,158,588...52,201,024
Ensembl chr 1:52,158,599...52,201,024 		JBrowse link
G Stra6l STRA6-like IEA MGI NCBI chr 4:45,818,940...45,887,010
Ensembl chr 4:45,848,664...45,887,008 		JBrowse link
G Tmem8b transmembrane protein 8B IEA MGI NCBI chr 4:43,668,971...43,692,668
Ensembl chr 4:43,668,971...43,692,668 		JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a IEA MGI NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 IEA MGI NCBI chr11:54,801,613...54,853,766
Ensembl chr11:54,801,611...54,853,743 		JBrowse link
G Tra2a transformer 2 alpha IEA MGI NCBI chr 6:49,220,855...49,241,182
Ensembl chr 6:49,220,858...49,240,967 		JBrowse link
G Usp16 ubiquitin specific peptidase 16 IEA MGI NCBI chr16:87,251,833...87,280,403
Ensembl chr16:87,251,591...87,280,405 		JBrowse link
G Zfp398 zinc finger protein 398 IEA MGI NCBI chr 6:47,812,567...47,850,476
Ensembl chr 6:47,812,595...47,850,471 		JBrowse link
G Zswim1 zinc finger SWIM-type containing 1 IEA MGI NCBI chr 2:164,664,933...164,668,791
Ensembl chr 2:164,664,606...164,668,791 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16532
    hematopoietic system phenotype 5355
      abnormal hematopoietic system morphology/development 4896
        abnormal bone marrow cell morphology/development 796
          abnormal myeloblast morphology/development 347
            abnormal basophil morphology 108
              abnormal basophil cell number 108
                decreased basophil cell number + 20
                increased basophil cell number 90
Path 2
Term Annotations click to browse term
  mammalian phenotype 16532
    hematopoietic system phenotype 5355
      abnormal hematopoietic system morphology/development 4896
        abnormal hematopoietic cell morphology 4074
          abnormal leukocyte morphology 2722
            abnormal myeloid leukocyte morphology 1400
              abnormal granulocyte morphology 885
                abnormal granulocyte number 852
                  abnormal basophil cell number 108
                    decreased basophil cell number + 20
                    increased basophil cell number 90
paths to the root