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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased colon tumor incidence
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Accession:MP:0012436 term browser browse the term
Definition:greater than the expected number of neoplasms in the colon, usually in the form of a distinct mass, in a specific population in a given time period
Synonyms:exact_synonym: increased colon tumour incidence
 related_synonym: Colon cancer
 xref: HP:0003003



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increased colon adenoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway IMP compared to treated females, mock treated males RGD PMID:17360473 RGD:1601201 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G ApcPirc APC, WNT signaling pathway regulator; polyposis in the rat colon IMP compared to treated females, mock treated males RGD PMID:17360473 RGD:1601201

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    digestive/alimentary phenotype 81
      abnormal digestive system morphology 59
        increased alimentary system tumor incidence 28
          increased gastrointestinal tumor incidence 17
            increased colon tumor incidence 15
              increased colon adenoma incidence 14
              increased colon hamartoma incidence 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    neoplasm 244
      abnormal tumor susceptibility 236
        abnormal tumor incidence 225
          abnormal organ/body region tumor incidence 189
            increased organ/body region tumor incidence 139
              increased alimentary system tumor incidence 28
                increased gastrointestinal tumor incidence 17
                  increased colon tumor incidence 15
                    increased colon adenoma incidence 14
                    increased colon hamartoma incidence 0
paths to the root