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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased partial thromboplastin time
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Accession:MP:0012359 term browser browse the term
Definition:increased amount of time it takes blood to clot after the addition of phospholipid, calcium, and an activator, e.g., silica, kaolin; measure of the quality of the intrinsic and common coagulation pathways
Synonyms:exact_synonym: increased aPTT;   increased activated thromboplastin time;   prolonged activated partial thromboplastin time


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increased partial thromboplastin time term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F8 coagulation factor VIII IMP as compared to wild type Sprague Dawley RGD PMID:24931420 RGD:11530071 NCBI chr18:140,848...172,330
Ensembl chr18:140,955...171,857 		JBrowse link
G F8em1Sage coagulation factor VIII, procoagulant component; zinc finger nuclease induced mutant1, Sage IMP RGD PMID:24931420 RGD:11530071
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  mammalian phenotype 5374
    homeostasis/metabolism phenotype 1396
      abnormal homeostasis 1299
        abnormal blood homeostasis 743
          abnormal hemostasis 18
            abnormal blood coagulation 17
              abnormal partial thromboplastin time 5
                increased partial thromboplastin time 5
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