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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:impaired learning
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Accession:MP:0012315 term browser browse the term
Definition:impaired ability to aquire lasting change in behavior that is the result of experience


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impaired learning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shank2 SH3 and multiple ankyrin repeat domains 2 IMP RGD PMID:29970986 RGD:126790534 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394 		JBrowse link
G Shank2em13Sage SH3 and multiple ankyrin repeat domains 2; ZFN induced mutant13, Sage IMP RGD PMID:29970986 RGD:126790534
G Ube3a ubiquitin protein ligase E3A IMP RGD PMID:32066685 RGD:126790466 NCBI chr 1:110,070,260...110,161,675
Ensembl chr 1:110,070,480...110,157,250 		JBrowse link
G Ube3aem1Jue ubiquitin protein ligase E3A; CRISPR/Cas9 induced mutant1, Jue IMP RGD PMID:32066685 RGD:126790466
impaired conditioned taste aversion behavior term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor sexual_dimorphism IMP RGD PMID:30769105 RGD:407419883 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ahrem2Sage aryl hydrocarbon receptor; ZFN induced mutant2, Sage sexual_dimorphism IMP RGD PMID:30769105 RGD:407419883
impaired discrimination learning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrxn1 neurexin 1 sexual_dimorphism IMP compared to wild type male RGD PMID:25420124 RGD:12914797 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Nrxn1em1 neurexin 1; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs sexual_dimorphism IMP compared to wild type male RGD PMID:25420124 RGD:12914797
impaired spatial learning term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1c calcium voltage-gated channel subunit alpha1 C sexual_dimorphism IMP compared to female wild-type RGD PMID:29800644 RGD:42724470 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cacna1cem1Sage calcium voltage-gated channel subunit alpha1 C; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs sexual_dimorphism IMP compared to female wild-type RGD PMID:29800644 RGD:42724470
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit IMP RGD PMID:17055644 RGD:151708697 NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IMP RGD PMID:28894415 PMID:36536454 PMID:38378836 RGD:38501107, RGD:401976434, RGD:401976422 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Fmr1em1Mzhe FMRP translational regulator 1; CRISPR/Cas9 induced mutant1, Mzhe IMP RGD PMID:28894415 RGD:38501107
G Fmr1em1Sage FMRP translational regulator 1; zinc finger nuclease induced mutant 1, Sigma Advanced Genetic Engineering Labs IMP RGD PMID:36536454 RGD:401976434
G Fmr1em2Mcwi FMRP translational regulator 1; CRISPR/Cas9 induced mutant 2, Medical College of Wisconsin IMP RGD PMID:38378836 RGD:401976422
G Gad1 glutamate decarboxylase 1 IMP RGD PMID:33293518 RGD:158012686 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad1em15Yyan glutamate decarboxylase 1; CRISPR/Cas9 induced mutant 15, Yyan IMP RGD PMID:33293518 RGD:158012686
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:11112797 RGD:2292520 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G KitWs KIT proto-oncogene receptor tyrosine kinase; mutant 1 IMP RGD PMID:11112797 RGD:2292520
G Ngly1 N-glycanase 1 IMP RGD PMID:32259258 RGD:39457703 NCBI chr15:9,153,738...9,210,228
Ensembl chr15:9,153,738...9,204,630 		JBrowse link
G Ngly1em1Ta N-glycanase 1; CRISPR/Cas9 induced mutant 1, Ta IMP RGD PMID:32259258 RGD:39457703
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5422
    behavior/neurological phenotype 614
      abnormal behavior 613
        abnormal cognition 127
          abnormal learning/memory/conditioning 124
            impaired learning 41
              impaired avoidance learning behavior + 8
              impaired discrimination learning + 3
              impaired spatial learning 24
paths to the root