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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:decreased susceptibility to hypertension
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Accession:MP:0012046 term browser browse the term
Definition:less likely than normal to develop sustained high blood pressure at a level that is likely to result in cardiovascular disease and/or other pathological states



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decreased susceptibility to hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 IMP RGD PMID:23753405 RGD:13782272 NCBI chr 8:30,779,883...30,808,607
Ensembl chr 8:30,753,617...30,813,796
JBrowse link
G Kcnj1em1Kasu potassium voltage-gated channel subfamily J member 1; ZFN induced mutant 1,Kasu IMP RGD PMID:23753405 RGD:13782272
G Ncf2 neutrophil cytosolic factor 2 IMP RGD PMID:22326221 RGD:9587793 NCBI chr13:64,955,502...64,986,289
Ensembl chr13:64,955,503...64,986,277
JBrowse link
G Ncf2em1Mcwi neutrophil cytosolic factor 2; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:22326221 RGD:9587793
G Nox4 NADPH oxidase 4 induced IMP compared to SS/JrHsdMcwi RGD PMID:26644237 PMID:26644237 RGD:11085830, RGD:11085830 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Nox4em2Mcwi NADPH oxidase 4; zinc finger nuclease induced mutant 2, Medical College of Wisconsin induced IMP compared to SS/JrHsdMcwi RGD PMID:26644237 PMID:26644237 RGD:11085830, RGD:11085830
G Plekha7 pleckstrin homology domain containing A7 IMP compared to wild type RGD PMID:25136115 PMID:25136115 RGD:11079199, RGD:11079199 NCBI chr 1:170,364,524...170,547,843
Ensembl chr 1:170,365,135...170,547,775
JBrowse link
G Plekha7em4Mcwi pleckstrin homology domain containing, family A member 7; zinc finger nuclease induced mutant 4, Medical College of Wisconsin IMP compared to wild type RGD PMID:25136115 PMID:25136115 RGD:11079199, RGD:11079199
G Sh2b3 SH2B adaptor protein 3 IMP RGD PMID:25776069 RGD:13442483 NCBI chr12:34,749,849...34,753,616
Ensembl chr12:34,731,911...34,753,616
JBrowse link
G Sh2b3em1Mcwi SH2B adaptor protein 3; zinc finger nuclease induced mutant 1, Medical College of Wisconsin IMP RGD PMID:25776069 RGD:13442483

Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 5369
    cardiovascular system phenotype 1356
      abnormal cardiovascular system physiology 1132
        abnormal systemic arterial blood pressure 991
          increased systemic arterial blood pressure 630
            hypertension 175
              decreased susceptibility to hypertension 30
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