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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal podocyte polarity
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Accession:MP:0011870 term browser browse the term
Definition:any anomaly in the establishment or maintenance of podocyte cell polarity; podocytes exhibit polarity along at least two axes: (i) an apical-basal axis perpendicular to the glomerular basement membrane in which the apical and basolateral membrane domains of the podocyte are separated by a boundary created by the intercellular junctions of the foot process and (ii) a second plane parallel to the basement membrane that determines the unique orientation of interdigitating foot processes



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  mammalian phenotype 5419
    renal/urinary system phenotype 649
      abnormal renal/urinary system morphology 279
        abnormal kidney morphology 272
          abnormal nephron morphology 118
            abnormal renal corpuscle morphology 108
              abnormal renal glomerular capsule morphology 8
                abnormal glomerular capsule visceral layer morphology 8
                  abnormal podocyte morphology 8
                    abnormal podocyte polarity 0
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