Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal glomerular filtration barrier morphology
go back to main search page
Accession:MP:0011855 term browser browse the term
Definition:any structural anomaly of the highly specialized blood filtration interface that displays a high conductance to small and midsized solutes in plasma but retains relative impermeability to macromolecules; its integrity is maintained by physicochemical and signalling interplay among its three core constituents -- the fenestrated endothelium of the glomerular capillaries, the glomerular basement membrane, and the filtration slits of the visceral epithelial cell (podocyte)
Synonyms:exact_synonym: abnormal GFB morphology



show annotations for term's descendants           Sort by:
abnormal glomerular filtration barrier morphology term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IMP RGD PMID:27465994 RGD:12911217 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:27465994 RGD:12911217

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5400
    renal/urinary system phenotype 646
      abnormal renal/urinary system morphology 276
        abnormal kidney morphology 269
          abnormal nephron morphology 115
            abnormal renal corpuscle morphology 105
              abnormal renal glomerulus morphology 103
                abnormal glomerular filtration barrier morphology 4
paths to the root