abnormal seminiferous tubule epithelium morphology - Ontology Report

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MAMMALIAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	abnormal seminiferous tubule epithelium morphology	go back to main search page
Accession:	MP:0011750	browse the term
Definition:	any structural anomaly of the stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule
Synonyms:	exact_synonym:	abnormal male germinal epithelium morphology; abnormal seminiferous epithelium morphology; abnormal seminiferous tubule epithelial tissue morphology; abnormal seminiferous tubule wall morphology
	alt_id:	MP:0006304

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Genes (2) Strains (2)

decreased Sertoli cell number

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Wwox

WW domain-containing oxidoreductase

IAGP

compared to wild type and heterozygotes

RGD

PMID:18676360

RGD:150429974

NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391

Wwox^lde

WW domain-containing oxidoreductase; lde mutant

IAGP

compared to wild type and heterozygotes

RGD

PMID:18676360

RGD:150429974

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	5380
reproductive system phenotype	129
abnormal reproductive system morphology	97
abnormal sex gland morphology	67
abnormal male reproductive gland morphology	58
abnormal testis morphology	46
abnormal seminiferous tubule morphology	12
abnormal seminiferous tubule epithelium morphology	4
abnormal Sertoli cell barrier morphology	0
abnormal Sertoli cell morphology +	4
abnormal ectoplasmic specialization morphology	0
Path 2
Term	Annotations
mammalian phenotype	5380
reproductive system phenotype	129
abnormal reproductive system morphology	97
abnormal male reproductive system morphology	66
abnormal male genitalia morphology	66
abnormal internal male genitalia morphology	58
abnormal testis morphology	46
abnormal seminiferous tubule morphology	12
abnormal seminiferous tubule epithelium morphology	4
abnormal Sertoli cell barrier morphology	0
abnormal Sertoli cell morphology +	4
abnormal ectoplasmic specialization morphology	0

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MAMMALIAN PHENOTYPE - ANNOTATIONS