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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:absent mast cells
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Accession:MP:0011696 term browser browse the term
Definition:any structural anomaly of a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation; progenitors leave bone marrow and mature in connective and mucosal tissue; mature mast cells are found in all tissues, except the bloodstream.



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absent mast cells term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase IMP RGD PMID:1912576 RGD:5133424 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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G KitWs KIT proto-oncogene receptor tyrosine kinase; mutant 1 IMP RGD PMID:1912576 RGD:5133424

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5401
    immune system phenotype 502
      abnormal immune system morphology 194
        abnormal immune system cell morphology 154
          abnormal leukocyte morphology 154
            abnormal leukocyte cell number 138
              decreased leukocyte cell number 90
                decreased granulocyte number 14
                  decreased mast cell number 3
                    absent mast cells 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 5401
    hematopoietic system phenotype 250
      abnormal hematopoietic system morphology/development 230
        abnormal hematopoietic cell morphology 186
          abnormal myeloid cell morphology 108
            abnormal myeloid leukocyte morphology 70
              abnormal granulocyte morphology 43
                abnormal granulocyte number 43
                  abnormal mast cell number 5
                    decreased mast cell number 3
                      absent mast cells 3
paths to the root