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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal glomerular capsule visceral layer morphology
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Accession:MP:0011497 term browser browse the term
Definition:any structural anomaly of the inner layer of the glomerular capsule surrounding the capillary endothelial cells and composed of highly specialized epithelial cells (podocytes) that are separated by filtration slits; the visceral layer is separated from the outer parietal layer by the urinary space (also known as the Bowman's or capsular space)
Synonyms:exact_synonym: abnormal Bowman's visceral epithelium morphology;   abnormal visceral epithelium of Bowman's capsule;   abnormal visceral layer of Bowman's capsule;   abnormal visceral layer of glomerular capsule



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podocyte foot process effacement term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lepr leptin receptor IMP RGD PMID:27465994 RGD:12911217 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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G Leprem2Mcwi leptin receptor; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:27465994 RGD:12911217

Term paths to the root
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  mammalian phenotype 5419
    renal/urinary system phenotype 649
      abnormal renal/urinary system morphology 279
        abnormal kidney morphology 272
          abnormal nephron morphology 118
            abnormal renal corpuscle morphology 108
              abnormal renal glomerular capsule morphology 8
                abnormal glomerular capsule visceral layer morphology 8
                  abnormal podocyte morphology + 8
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