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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased excitatory postsynaptic current amplitude
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Accession:MP:0011270 term browser browse the term
Definition:reduction in the size (height or maximum displacement) of the evoked excitatory postsynaptic current wave
Synonyms:exact_synonym: decreased excitatory post-synaptic current amplitude;   reduced excitatory post-synaptic current amplitude;   reduced excitatory postsynaptic current amplitude


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decreased excitatory postsynaptic current amplitude term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit IAGP MGI PMID:12040045 PMID:28688851 NCBI chr 8:85,065,257...85,366,880
Ensembl chr 8:85,065,268...85,366,875 		JBrowse link
G Cacng2 calcium channel, voltage-dependent, gamma subunit 2 IAGP MGI PMID:20529126 NCBI chr15:77,876,119...78,004,420
Ensembl chr15:77,875,948...78,004,228 		JBrowse link
G Cacng7 calcium channel, voltage-dependent, gamma subunit 7 IAGP MGI PMID:20529126 NCBI chr 7:3,381,341...3,416,737
Ensembl chr 7:3,381,471...3,416,737 		JBrowse link
G Cadps Ca2+-dependent secretion activator IAGP MGI PMID:18022372 PMID:24174665 NCBI chr14:9,646,424...10,097,203
Ensembl chr14:9,646,684...10,097,200 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV IAGP MGI PMID:11069976 NCBI chr18:33,067,995...33,328,820
Ensembl chr18:33,067,984...33,324,281 		JBrowse link
G Cbln1 cerebellin 1 precursor protein IAGP MGI PMID:16234806 NCBI chr 8:88,195,481...88,199,220
Ensembl chr 8:88,195,033...88,199,237 		JBrowse link
G Cbln1os cerebellin 1 precursor protein opposite strand IAGP MGI PMID:33762741 NCBI chr 8:88,199,440...88,252,182
Ensembl chr 8:88,186,433...88,262,001 		JBrowse link
G Clta clathrin light chain A IAGP MGI PMID:32907943 NCBI chr 4:44,003,816...44,032,846
Ensembl chr 4:44,004,452...44,032,846 		JBrowse link
G Cplx1 complexin 1 IAGP MGI PMID:18505837 PMID:19553439 NCBI chr 5:108,666,420...108,697,893
Ensembl chr 5:108,666,420...108,697,890 		JBrowse link
G Cplx2 complexin 2 IAGP MGI PMID:18505837 NCBI chr13:54,455,447...54,531,736
Ensembl chr13:54,519,162...54,531,730 		JBrowse link
G Cplx3 complexin 3 IAGP MGI PMID:18505837 NCBI chr 9:57,507,275...57,513,564
Ensembl chr 9:57,507,275...57,513,564 		JBrowse link
G Dlg3 discs large MAGUK scaffold protein 3 IAGP MGI PMID:27466188 NCBI chr  X:99,811,200...99,862,016
Ensembl chr  X:99,811,328...99,862,016 		JBrowse link
G Dner delta/notch-like EGF repeat containing IAGP MGI PMID:16298139 NCBI chr 1:84,347,560...84,673,942
Ensembl chr 1:84,347,560...84,673,942 		JBrowse link
G Dnm1 dynamin 1 IAGP MGI PMID:21689597 NCBI chr 2:32,198,483...32,243,361
Ensembl chr 2:32,198,483...32,243,350 		JBrowse link
G Dnm3 dynamin 3 IAGP MGI PMID:21689597 NCBI chr 1:161,810,022...162,305,890
Ensembl chr 1:161,810,022...162,305,603 		JBrowse link
G Gprasp2 G protein-coupled receptor associated sorting protein 2 IAGP MGI PMID:30926797 NCBI chr  X:134,739,786...134,745,480
Ensembl chr  X:134,739,783...134,745,479 		JBrowse link
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) IAGP MGI PMID:23277569 NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199 		JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) IAGP MGI PMID:20357110 NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509 		JBrowse link
G Htt huntingtin IAGP MGI PMID:24728353 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878 		JBrowse link
G Igsf11 immunoglobulin superfamily, member 11 IAGP MGI PMID:26595655 NCBI chr16:38,712,840...38,847,521
Ensembl chr16:38,713,033...38,847,521 		JBrowse link
G Ip6k1 inositol hexaphosphate kinase 1 IAGP MGI PMID:32252022 NCBI chr 9:107,879,847...107,925,981
Ensembl chr 9:107,879,700...107,925,981 		JBrowse link
G Lhx5as1 LIM homeobox 5, antisense 1 IAGP MGI PMID:35196493 NCBI chr 5:120,557,721...120,569,832
Ensembl chr 5:120,557,719...120,569,865 		JBrowse link
G Lrrc4b leucine rich repeat containing 4B IAGP MGI PMID:31166939 NCBI chr 7:44,091,911...44,112,775
Ensembl chr 7:44,078,442...44,112,775 		JBrowse link
G Lrrtm1 leucine rich repeat transmembrane neuronal 1 IAGP MGI PMID:29784826 NCBI chr 6:77,192,762...77,236,898
Ensembl chr 6:77,219,672...77,234,774 		JBrowse link
G Lrrtm2 leucine rich repeat transmembrane neuronal 2 IAGP MGI PMID:29784826 NCBI chr18:35,342,056...35,348,077
Ensembl chr18:35,342,056...35,348,077 		JBrowse link
G Lrrtm3 leucine rich repeat transmembrane neuronal 3 IAGP MGI PMID:26776509 NCBI chr10:63,764,276...63,926,034
Ensembl chr10:63,764,251...63,926,056 		JBrowse link
G Mecp2 methyl CpG binding protein 2 IAGP MGI PMID:17920015 NCBI chr  X:73,070,198...73,129,296
Ensembl chr  X:73,070,198...73,129,296 		JBrowse link
G Nedd4 neural precursor cell expressed, developmentally down-regulated 4 IAGP MGI PMID:20159449 NCBI chr 9:72,569,613...72,657,133
Ensembl chr 9:72,569,628...72,657,134 		JBrowse link
G Nlgn1 neuroligin 1 IAGP MGI PMID:26291161 NCBI chr 3:25,475,972...26,387,504
Ensembl chr 3:25,480,379...26,386,609 		JBrowse link
G Nlgn2 neuroligin 2 IAGP MGI PMID:26291161 NCBI chr11:69,713,949...69,728,610
Ensembl chr11:69,713,948...69,728,610 		JBrowse link
G Nlgn3 neuroligin 3 IAGP MGI PMID:26291161 NCBI chr  X:100,342,785...100,364,956
Ensembl chr  X:100,342,774...100,369,569 		JBrowse link
G Nrxn1 neurexin I IAGP MGI PMID:12827191 NCBI chr17:90,341,072...91,400,587
Ensembl chr17:90,341,059...91,400,499 		JBrowse link
G Nrxn2 neurexin II IAGP MGI PMID:12827191 NCBI chr19:6,468,786...6,583,247
Ensembl chr19:6,468,761...6,594,199 		JBrowse link
G Nrxn3 neurexin III IAGP MGI PMID:12827191 NCBI chr12:88,689,454...90,301,709
Ensembl chr12:88,689,646...90,301,709 		JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 IAGP MGI PMID:21926968 NCBI chr17:27,874,565...27,930,092
Ensembl chr17:27,874,483...27,930,456 		JBrowse link
G Prrt2 proline-rich transmembrane protein 2 IAGP MGI PMID:32891704 NCBI chr 7:126,616,707...126,620,800
Ensembl chr 7:126,616,703...126,620,383 		JBrowse link
G Ptf1a pancreas specific transcription factor, 1a IAGP MGI PMID:24174665 NCBI chr 2:19,450,474...19,452,312
Ensembl chr 2:19,450,474...19,452,312 		JBrowse link
G Rimbp2 RIMS binding protein 2 IAGP MGI PMID:27671655 NCBI chr 5:128,834,852...129,030,636
Ensembl chr 5:128,834,855...129,030,550 		JBrowse link
G Rps23rg1 ribosomal protein S23, retrogene 1 IAGP MGI PMID:30292394 NCBI chr 8:3,617,998...3,634,776
Ensembl chr 8:3,617,990...3,634,939 		JBrowse link
G Sez6 seizure related gene 6 IAGP MGI PMID:16814779 NCBI chr11:77,821,403...77,869,874
Ensembl chr11:77,821,626...77,869,874 		JBrowse link
G Sez6l seizure related 6 homolog like IAGP MGI PMID:16814779 NCBI chr 5:112,567,020...112,726,401
Ensembl chr 5:112,567,017...112,725,051 		JBrowse link
G Sez6l2 seizure related 6 homolog like 2 IAGP MGI PMID:16814779 NCBI chr 7:126,549,665...126,569,782
Ensembl chr 7:126,549,735...126,569,778 		JBrowse link
G Sh3gl1 SH3-domain GRB2-like 1 IAGP MGI PMID:22099461 NCBI chr17:56,323,750...56,343,659
Ensembl chr17:56,323,750...56,343,635 		JBrowse link
G Sh3gl2 SH3-domain GRB2-like 2 IAGP MGI PMID:22099461 NCBI chr 4:85,123,663...85,307,617
Ensembl chr 4:85,123,363...85,557,432 		JBrowse link
G Sh3gl3 SH3-domain GRB2-like 3 IAGP MGI PMID:22099461 NCBI chr 7:81,824,581...81,956,618
Ensembl chr 7:81,823,588...81,956,627 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 IAGP MGI PMID:35385725 NCBI chr 8:61,677,117...61,918,327
Ensembl chr 8:61,676,906...61,849,105 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 IAGP MGI PMID:26687841 PMID:26886798 NCBI chr15:89,376,929...89,444,464
Ensembl chr15:89,383,826...89,444,464 		JBrowse link
G Snap91 synaptosomal-associated protein 91 IAGP MGI PMID:26412491 NCBI chr 9:86,647,976...86,762,766
Ensembl chr 9:86,647,976...86,762,707 		JBrowse link
G Stx1a syntaxin 1A (brain) IAGP MGI PMID:24587181 NCBI chr 5:135,051,473...135,079,954
Ensembl chr 5:135,052,336...135,079,954 		JBrowse link
G Stx1b syntaxin 1B IAGP MGI PMID:24587181 NCBI chr 7:127,403,072...127,423,703
Ensembl chr 7:127,403,072...127,423,721 		JBrowse link
G Syt1 synaptotagmin I IAGP MGI PMID:11242035 PMID:21040848 NCBI chr10:108,333,511...108,846,852
Ensembl chr10:108,333,511...108,846,843 		JBrowse link
G Thrb thyroid hormone receptor beta IAGP MGI PMID:24932806 NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435 		JBrowse link
G Tmem108 transmembrane protein 108 IAGP MGI PMID:28096412 NCBI chr 9:103,360,135...103,639,099
Ensembl chr 9:103,360,146...103,639,036 		JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 IAGP MGI PMID:24599464 NCBI chr 3:54,063,441...54,225,892
Ensembl chr 3:54,063,456...54,225,892 		JBrowse link
G Zdhhc7 zinc finger, DHHC domain containing 7 IAGP MGI PMID:31183559 NCBI chr 8:120,807,834...120,828,211
Ensembl chr 8:120,807,629...120,828,221 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 17088
    nervous system phenotype 4651
      abnormal nervous system physiology 2729
        abnormal synaptic physiology 1238
          abnormal synaptic transmission 1229
            abnormal CNS synaptic transmission 1131
              abnormal excitatory postsynaptic currents 180
                abnormal excitatory postsynaptic current amplitude 77
                  decreased excitatory postsynaptic current amplitude 55
paths to the root