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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased CD4-positive, alpha-beta memory T cell number
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Accession:MP:0010836 term browser browse the term
Definition:reduced number of CD4-positive, alpha-beta long-lived T cells with the phenotype CD45RO-positive and CD127-positive, or also described as being CD25-negative, CD44-high, and CD122- high
Synonyms:exact_synonym: decreased CD4-positive, alpha-beta memory T lymphocyte number;   reduced CD4-positive, alpha-beta memory T lymphocyte number;   reduced CD4-positive, alpha-beta memory T-cell number
 related_synonym: decreased T4.Mem.Sp number;   reduced T4.Mem.Sp number
 xref: CL:0000897


show annotations for term's descendants           Sort by:
decreased CD4-positive, alpha-beta memory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2a1a B cell leukemia/lymphoma 2 related protein A1a IAGP MGI PMID:28085150 NCBI chr 9:88,838,973...88,844,469
Ensembl chr 9:88,838,953...88,844,472 		JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b IAGP MGI PMID:28085150 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880 		JBrowse link
G Bcl2a1d B cell leukemia/lymphoma 2 related protein A1d IAGP MGI PMID:28085150 NCBI chr 9:88,605,341...88,613,903
Ensembl chr 9:88,605,338...88,613,967 		JBrowse link
G Il27 interleukin 27 IEA MGI NCBI chr 7:126,188,181...126,194,197
Ensembl chr 7:126,188,182...126,194,113 		JBrowse link
G Irf5 interferon regulatory factor 5 IEA MGI NCBI chr 6:29,526,129...29,541,874
Ensembl chr 6:29,526,624...29,541,870 		JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha IAGP MGI PMID:21333553 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IEA MGI NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Septin9 septin 9 IAGP MGI PMID:23644740 NCBI chr11:117,090,487...117,253,151
Ensembl chr11:117,090,487...117,253,151 		JBrowse link
G Slc1a5 solute carrier family 1 (neutral amino acid transporter), member 5 IAGP MGI PMID:24792914 NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199 		JBrowse link
G Traf3ip3 TRAF3 interacting protein 3 IAGP MGI PMID:26195727 NCBI chr 1:192,857,812...192,883,854
Ensembl chr 1:192,857,761...192,884,011 		JBrowse link
G Zfp335 zinc finger protein 335 IAGP MGI PMID:25343476 NCBI chr 2:164,733,802...164,756,034
Ensembl chr 2:164,733,802...164,753,677 		JBrowse link
decreased central memory CD4-positive, alpha-beta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2a1a B cell leukemia/lymphoma 2 related protein A1a IAGP MGI PMID:28085150 NCBI chr 9:88,838,973...88,844,469
Ensembl chr 9:88,838,953...88,844,472 		JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b IAGP MGI PMID:28085150 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880 		JBrowse link
G Bcl2a1d B cell leukemia/lymphoma 2 related protein A1d IAGP MGI PMID:28085150 NCBI chr 9:88,605,341...88,613,903
Ensembl chr 9:88,605,338...88,613,967 		JBrowse link
G Card11 caspase recruitment domain family, member 11 IEA MGI NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Cd44 CD44 antigen IEA MGI NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Ikbkb inhibitor of kappaB kinase beta IEA MGI NCBI chr 8:23,149,228...23,196,605
Ensembl chr 8:23,149,228...23,196,605 		JBrowse link
G Klhl6 kelch-like 6 IEA MGI NCBI chr16:19,765,242...19,801,766
Ensembl chr16:19,765,246...19,801,787 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 IEA MGI NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Rel reticuloendotheliosis oncogene IEA MGI NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970 		JBrowse link
decreased effector memory CD4-positive, alpha-beta T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2a1a B cell leukemia/lymphoma 2 related protein A1a IAGP MGI PMID:28085150 NCBI chr 9:88,838,973...88,844,469
Ensembl chr 9:88,838,953...88,844,472 		JBrowse link
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b IAGP MGI PMID:28085150 NCBI chr 9:89,081,326...89,089,891
Ensembl chr 9:89,081,262...89,089,880 		JBrowse link
G Bcl2a1d B cell leukemia/lymphoma 2 related protein A1d IAGP MGI PMID:28085150 NCBI chr 9:88,605,341...88,613,903
Ensembl chr 9:88,605,338...88,613,967 		JBrowse link
G Card11 caspase recruitment domain family, member 11 IEA MGI NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Cd44 CD44 antigen IEA MGI NCBI chr 2:102,641,486...102,732,014
Ensembl chr 2:102,641,486...102,732,010 		JBrowse link
G Ebf1 early B cell factor 1 IEA MGI NCBI chr11:44,502,738...44,898,923
Ensembl chr11:44,508,144...44,898,918 		JBrowse link
G Myd88 myeloid differentiation primary response gene 88 IAGP MGI PMID:26136579 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477 		JBrowse link
G Nek8 NIMA (never in mitosis gene a)-related expressed kinase 8 IEA MGI NCBI chr11:78,056,932...78,067,501
Ensembl chr11:78,056,932...78,067,501 		JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 IEA MGI NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308 		JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide IEA MGI NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C IEA MGI NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Rel reticuloendotheliosis oncogene IEA MGI NCBI chr11:23,686,847...23,720,969
Ensembl chr11:23,686,847...23,720,970 		JBrowse link
G Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) IEA MGI NCBI chr17:34,423,453...34,435,295
Ensembl chr17:34,422,501...34,435,295 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16965
    immune system phenotype 5704
      abnormal immune system morphology 4076
        abnormal immune system cell morphology 2841
          abnormal leukocyte morphology 2820
            abnormal leukocyte cell number 2533
              decreased leukocyte cell number 1647
                decreased lymphocyte cell number 1274
                  decreased T cell number 777
                    decreased memory T cell number 64
                      decreased CD4-positive, alpha-beta memory T cell number 22
                        decreased central memory CD4-positive, alpha-beta T cell number 9
                        decreased effector memory CD4-positive, alpha-beta T cell number 13
Path 2
Term Annotations click to browse term
  mammalian phenotype 16965
    immune system phenotype 5704
      abnormal immune system morphology 4076
        abnormal immune system cell morphology 2841
          abnormal leukocyte morphology 2820
            abnormal mononuclear cell morphology 2274
              abnormal lymphocyte morphology 1841
                abnormal T cell morphology 1172
                  abnormal effector T cell morphology 855
                    abnormal CD4-positive, alpha beta T cell morphology 605
                      abnormal CD4-positive, alpha-beta T cell number 520
                        decreased CD4-positive, alpha-beta T cell number 337
                          decreased CD4-positive, alpha-beta memory T cell number 22
                            decreased central memory CD4-positive, alpha-beta T cell number 9
                            decreased effector memory CD4-positive, alpha-beta T cell number 13
paths to the root