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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased type II pneumocyte number
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Accession:MP:0010811 term browser browse the term
Definition:reduced number of the granular and roughly cuboidal cells typically found at the alveolar-septal junction that modulate the fluid surrounding the alveolar epithelium by secreting and recycling surfactants, and also contribute to tissue repair and can differentiate after injury into a type I pneumocyte; type II cells cover a much smaller surface area than type I cells (less than 5 percent), but are much more numerous and contain lamellar bodies on the apical surface where surfactant is stored
Synonyms:exact_synonym: decreased AT2 number;   decreased ATII number;   decreased Cuboidal type II cell number;   decreased Great alveolar cell number;   decreased Lung type 2 cell number;   decreased TII number;   decreased granular pneumocyte number;   decreased type 2 alveolar epithelial cell number;   decreased type 2 alveolocyte number;   decreased type 2 pneumocyte number;   decreased type II alveolar epithelial cell number;   decreased type II alveolocyte number;   decreased type II cell number;   decreased type II pneumocytes;   decreased type II pneumonocyte number;   reduced AT2 number;   reduced ATII number;   reduced Cuboidal type II cell number;   reduced Great alveolar cell number;   reduced Lung type 2 cell number;   reduced TII number;   reduced granular pneumocyte number;   reduced type 2 alveolar epithelial cell number;   reduced type 2 alveolocyte number;   reduced type 2 pneumocyte number;   reduced type II alveolar epithelial cell number;   reduced type II alveolocyte number;   reduced type II cell number;   reduced type II pneumocytes;   reduced type II pneumonocyte number
 related_synonym: decreased Lung type II cell number;   reduced Lung type II cell number
 xref: CL:0002063;   FMA:62501


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Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    respiratory system phenotype 47
      abnormal respiratory system morphology 33
        abnormal lung morphology 26
          abnormal lung epithelium morphology 6
            abnormal pulmonary alveolus epithelium morphology 6
              abnormal pulmonary alveolus epithelial cell morphology 6
                abnormal type II pneumocyte morphology 6
                  decreased type II pneumocyte number 0
                    absent type II pneumocytes 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    respiratory system phenotype 47
      abnormal respiratory system morphology 33
        abnormal lung morphology 26
          abnormal pulmonary alveolar system morphology 7
            abnormal pulmonary acinus morphology 7
              abnormal pulmonary alveolus morphology 7
                abnormal pulmonary alveolus epithelium morphology 6
                  abnormal pulmonary alveolus epithelial cell morphology 6
                    abnormal type II pneumocyte morphology 6
                      decreased type II pneumocyte number 0
                        absent type II pneumocytes 0
paths to the root