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Pathways

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased kidney tumor incidence
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Accession:MP:0010294 term browser browse the term
Definition:greater than the expected number of tumors originating in the kidney in a given population in a given time period
Synonyms:exact_synonym: increased kidney tumour incidence;   increased renal tumor incidence;   increased renal tumour incidence



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increased kidney tumor incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Flcn folliculin IAGP MGI PMID:19234517 NCBI chr11:59,682,234...59,706,138
Ensembl chr11:59,682,234...59,700,842
JBrowse link
G Fnip1 folliculin interacting protein 1 IAGP MGI PMID:25775561 NCBI chr11:54,328,071...54,409,067
Ensembl chr11:54,329,025...54,409,061
JBrowse link
G Fnip2 folliculin interacting protein 2 IAGP MGI PMID:25775561 NCBI chr 3:79,363,556...79,475,458
Ensembl chr 3:79,363,281...79,475,103
JBrowse link
G Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano IAGP MGI PMID:24732380 NCBI chr 6:113,044,389...113,054,205
Ensembl chr 6:113,043,843...113,054,294
JBrowse link
G Hat1 histone aminotransferase 1 IAGP MGI PMID:31290578 NCBI chr 2:71,219,604...71,271,966
Ensembl chr 2:71,219,302...71,271,966
JBrowse link
G Pcbp4 poly(rC) binding protein 4 IAGP MGI PMID:26915821 NCBI chr 9:106,330,181...106,341,211
Ensembl chr 9:106,330,490...106,341,211
JBrowse link
G Tsc2 TSC complex subunit 2 IAGP MGI PMID:18316403 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604
JBrowse link
G Wt1 WT1 transcription factor IAGP MGI PMID:24732380 NCBI chr 2:104,956,874...105,003,959
Ensembl chr 2:104,956,874...105,003,961
JBrowse link
increased renal carcinoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn1a cyclin dependent kinase inhibitor 1A IAGP MGI PMID:18598944 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn2c cyclin dependent kinase inhibitor 2C IAGP MGI PMID:10880462 NCBI chr 4:109,518,073...109,523,953
Ensembl chr 4:109,518,073...109,524,386
JBrowse link
G Dkc1 dyskeratosis congenita 1, dyskerin IAGP MGI PMID:12522253 NCBI chr  X:74,139,460...74,153,382
Ensembl chr  X:74,139,460...74,153,383
JBrowse link
G Fah fumarylacetoacetate hydrolase IAGP MGI PMID:18598944 NCBI chr 7:84,234,367...84,255,150
Ensembl chr 7:84,234,367...84,255,930
JBrowse link
G Flcn folliculin IAGP MGI PMID:18974783 NCBI chr11:59,682,234...59,706,138
Ensembl chr11:59,682,234...59,700,842
JBrowse link
G Nf2 neurofibromin 2 IAGP MGI PMID:10887156 PMID:15221010 PMID:19487675 NCBI chr11:4,715,845...4,799,544
Ensembl chr11:4,715,845...4,799,536
JBrowse link
G Pten phosphatase and tensin homolog IAGP MGI PMID:16488991 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Sptbn1 spectrin beta, non-erythrocytic 1 IAGP MGI PMID:20739274 NCBI chr11:30,049,395...30,218,384
Ensembl chr11:30,049,395...30,218,175
JBrowse link
G Tsc1 TSC complex subunit 1 IAGP MGI PMID:11438694 PMID:11875047 PMID:15888477 NCBI chr 2:28,531,005...28,581,183
Ensembl chr 2:28,531,240...28,581,179
JBrowse link
G Tsc2 TSC complex subunit 2 IAGP MGI PMID:10096549 PMID:10491404 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604
JBrowse link
increased renal cystadenoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC, WNT signaling pathway regulator IAGP MGI PMID:15550389 NCBI chr18:34,353,350...34,455,243
Ensembl chr18:34,353,977...34,455,605
JBrowse link
G Tsc1 TSC complex subunit 1 IAGP MGI PMID:11438694 PMID:11875047 PMID:15888477 NCBI chr 2:28,531,005...28,581,183
Ensembl chr 2:28,531,240...28,581,179
JBrowse link
G Tsc2 TSC complex subunit 2 IAGP MGI PMID:10491404 PMID:19357198 NCBI chr17:24,814,788...24,851,607
Ensembl chr17:24,814,790...24,851,604
JBrowse link
increased renal hamartoma incidence term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pkd1 polycystin 1, transient receptor potential channel interacting IAGP MGI PMID:23064367 NCBI chr17:24,767,657...24,815,457
Ensembl chr17:24,768,808...24,815,482
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16478
    renal/urinary system phenotype 2058
      abnormal renal/urinary system morphology 1711
        increased urinary system tumor incidence 31
          increased kidney tumor incidence 18
            increased renal carcinoma incidence 10
            increased renal cystadenoma incidence 3
            increased renal hamartoma incidence 1
            increased renal hemangioblastoma incidence 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 16478
    neoplasm 1326
      abnormal tumor susceptibility 1189
        abnormal tumor incidence 1168
          increased tumor incidence 1002
            increased organ/body region tumor incidence 842
              increased urinary system tumor incidence 31
                increased kidney tumor incidence 18
                  increased renal carcinoma incidence 10
                  increased renal cystadenoma incidence 3
                  increased renal hamartoma incidence 1
                  increased renal hemangioblastoma incidence 0
paths to the root