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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased gastrointestinal tumor incidence
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Accession:MP:0010279 term browser browse the term
Definition:greater than the expected number of tumors originating in the gastrointestinal system in a given population in a given time period
Synonyms:exact_synonym: increased gastrointestinal tract neoplasia incidence;   increased gastrointestinal tumour incidence
 related_synonym: Gastrointestinal carcinoma
 xref: HP:0002672


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increased colon adenoma incidence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway IMP compared to treated females, mock treated males RGD PMID:17360473 RGD:1601201 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G ApcPirc APC, WNT signaling pathway regulator; polyposis in the rat colon IMP compared to treated females, mock treated males RGD PMID:17360473 RGD:1601201
increased intestinal adenocarcinoma incidence term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apc APC regulator of WNT signaling pathway sexual_dimorphism IMP compared to treated females RGD PMID:17360473 RGD:1601201 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G ApcPirc APC, WNT signaling pathway regulator; polyposis in the rat colon sexual_dimorphism IMP compared to treated females RGD PMID:17360473 RGD:1601201
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5417
    digestive/alimentary phenotype 81
      abnormal digestive system morphology 59
        increased alimentary system tumor incidence 28
          increased gastrointestinal tumor incidence 17
            increased colon tumor incidence + 15
            increased duodenum glandular epithelium tumor incidence + 0
            increased gastrointestinal stromal tumor incidence 0
            increased intestinal adenocarcinoma incidence + 4
            increased intestinal adenoma incidence + 14
            increased intestinal hemangioma incidence 0
            increased pancreatic gastrinoma incidence 0
            increased stomach tumor incidence + 1
Path 2
Term Annotations click to browse term
  mammalian phenotype 5417
    neoplasm 244
      abnormal tumor susceptibility 236
        abnormal tumor incidence 225
          increased tumor incidence 166
            increased organ/body region tumor incidence 139
              increased alimentary system tumor incidence 28
                increased gastrointestinal tumor incidence 17
                  increased colon tumor incidence + 15
                  increased duodenum glandular epithelium tumor incidence + 0
                  increased gastrointestinal stromal tumor incidence 0
                  increased intestinal adenocarcinoma incidence + 4
                  increased intestinal adenoma incidence + 14
                  increased intestinal hemangioma incidence 0
                  increased pancreatic gastrinoma incidence 0
                  increased stomach tumor incidence + 1
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