Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal T follicular helper cell differentiation
go back to main search page
Accession:MP:0010188 term browser browse the term
Definition:atypical production of or inability to produce the CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cells located in follicles of secondary lymph nodes that expresses high levels of BCL-6, ICOS and PD1 and stimulate follicular B cells to undergo class-switching and antibody production
Synonyms:xref: CL:0002038



show annotations for term's descendants           Sort by:

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5400
    immune system phenotype 499
      abnormal immune system morphology 191
        abnormal immune system cell morphology 151
          abnormal leukopoiesis 18
            abnormal lymphopoiesis 18
              abnormal T cell differentiation 18
                abnormal CD4-positive T cell differentiation 4
                  abnormal T follicular helper cell differentiation 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5400
    hematopoietic system phenotype 247
      abnormal hematopoietic system morphology/development 227
        abnormal hematopoietic cell morphology 183
          abnormal leukocyte morphology 151
            abnormal mononuclear cell morphology 124
              abnormal lymphocyte morphology 99
                abnormal T cell morphology 69
                  abnormal effector T cell morphology 23
                    abnormal T-helper cell morphology 1
                      abnormal CD4-positive helper T cell morphology 1
                        abnormal T follicular helper cell morphology 0
                          abnormal T follicular helper cell differentiation 0
paths to the root