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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased T follicular helper cell number
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Accession:MP:0010186 term browser browse the term
Definition:greater number of the CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cells located in follicles of secondary lymph nodes that expresses high levels of BCL-6, ICOS and PD1 and stimulate follicular B cells to undergo class-switching and antibody production
Synonyms:xref: CL:0002038


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Path 1
Term Annotations click to browse term
  mammalian phenotype 5375
    immune system phenotype 493
      abnormal immune system morphology 188
        abnormal immune system cell morphology 148
          abnormal leukocyte morphology 148
            abnormal leukocyte cell number 135
              increased leukocyte cell number 65
                increased lymphocyte cell number 28
                  increased T cell number 18
                    increased T-helper cell number 1
                      increased T follicular helper cell number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5375
    immune system phenotype 493
      abnormal immune system morphology 188
        abnormal immune system cell morphology 148
          abnormal leukocyte morphology 148
            abnormal mononuclear cell morphology 121
              abnormal lymphocyte morphology 99
                abnormal T cell morphology 69
                  abnormal effector T cell morphology 23
                    abnormal CD4-positive, alpha beta T cell morphology 17
                      abnormal CD4-positive helper T cell morphology 1
                        abnormal T follicular helper cell morphology 0
                          abnormal T follicular helper cell number 0
                            increased T follicular helper cell number 0
paths to the root