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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:abnormal T follicular helper cell number
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Accession:MP:0010185 term browser browse the term
Definition:anomaly in the number of the CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cells located in follicles of secondary lymph nodes that expresses high levels of BCL-6, ICOS and PD1 and stimulate follicular B cells to undergo class-switching and antibody production
Synonyms:xref: CL:0002038


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Term Annotations click to browse term
  mammalian phenotype 5374
    immune system phenotype 492
      abnormal immune system morphology 187
        abnormal immune system cell morphology 147
          abnormal leukocyte morphology 147
            abnormal leukocyte cell number 134
              abnormal lymphocyte cell number 92
                abnormal T cell number 62
                  abnormal effector T cell number 1
                    abnormal T-helper cell number 1
                      abnormal T follicular helper cell number 0
                        decreased T follicular helper cell number 0
                        increased T follicular helper cell number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5374
    immune system phenotype 492
      abnormal immune system morphology 187
        abnormal immune system cell morphology 147
          abnormal leukocyte morphology 147
            abnormal mononuclear cell morphology 120
              abnormal lymphocyte morphology 98
                abnormal T cell morphology 68
                  abnormal alpha-beta T cell morphology 33
                    abnormal CD4-positive, alpha beta T cell morphology 17
                      abnormal CD4-positive helper T cell morphology 1
                        abnormal T follicular helper cell morphology 0
                          abnormal T follicular helper cell number 0
                            decreased T follicular helper cell number 0
                            increased T follicular helper cell number 0
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