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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:abnormal T follicular helper cell number
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Accession:MP:0010185 term browser browse the term
Definition:anomaly in the number of the CD4-positive, CXCR5-positive, CCR7-negative alpha-beta T cells located in follicles of secondary lymph nodes that expresses high levels of BCL-6, ICOS and PD1 and stimulate follicular B cells to undergo class-switching and antibody production
Synonyms:xref: CL:0002038



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Term Annotations click to browse term
  mammalian phenotype 5402
    immune system phenotype 502
      abnormal immune system morphology 194
        abnormal immune system cell morphology 154
          abnormal leukocyte morphology 154
            abnormal leukocyte cell number 138
              abnormal lymphocyte cell number 93
                abnormal T cell number 63
                  abnormal effector T cell number 1
                    abnormal T-helper cell number 1
                      abnormal T follicular helper cell number 0
                        decreased T follicular helper cell number 0
                        increased T follicular helper cell number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5402
    immune system phenotype 502
      abnormal immune system morphology 194
        abnormal immune system cell morphology 154
          abnormal leukocyte morphology 154
            abnormal mononuclear cell morphology 127
              abnormal lymphocyte morphology 99
                abnormal T cell morphology 69
                  abnormal alpha-beta T cell morphology 34
                    abnormal CD4-positive, alpha beta T cell morphology 17
                      abnormal CD4-positive helper T cell morphology 1
                        abnormal T follicular helper cell morphology 0
                          abnormal T follicular helper cell number 0
                            decreased T follicular helper cell number 0
                            increased T follicular helper cell number 0
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