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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number
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Accession:MP:0010168 term browser browse the term
Definition:a greater number of the CD4-positive, CD25-positive T cell subset which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release
Synonyms:exact_synonym: increased CD4-positive, CD25-positive, alpha-beta Treg number;   increased CD4-positive, CD25-positive, alpha-beta regulatory T lymphocyte number
 broad_synonym: increased suppressor T cell number;   increased suppressor T lymphocyte number
 xref: CL:0000792



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increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
S BBDP.ACI-(D2Mit8-D2Arb16)(D2Rat354-D2Rat69)/Sunn IAGP compared to BBDP/WorSunn RGD PMID:24920533 RGD:10043114 NCBI chr 2:143,657,411...190,602,963
NCBI chr 2:191,987,426...191,987,650
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Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5374
    immune system phenotype 492
      abnormal immune system morphology 187
        abnormal immune system cell morphology 147
          abnormal leukocyte morphology 147
            abnormal leukocyte cell number 134
              abnormal lymphocyte cell number 92
                abnormal T cell number 62
                  abnormal regulatory T cell number 7
                    increased regulatory T cell number 4
                      increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number 1
                        increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number 0
                        increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5374
    immune system phenotype 492
      abnormal immune system morphology 187
        abnormal immune system cell morphology 147
          abnormal leukocyte morphology 147
            abnormal mononuclear cell morphology 120
              abnormal lymphocyte morphology 98
                abnormal T cell morphology 68
                  abnormal effector T cell morphology 23
                    abnormal CD4-positive, alpha beta T cell morphology 17
                      abnormal CD4-positive, alpha-beta T cell number 13
                        increased CD4-positive, alpha-beta T cell number 5
                          increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number 1
                            increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number 0
                            increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number 0
paths to the root