decreased DN3 thymocyte number - Ontology Report - Rat Genome Database

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MAMMALIAN PHENOTYPE - ANNOTATIONS	{{ watchLinkText }}
The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:	decreased DN3 thymocyte number	go back to main search page
Accession:	MP:0010134	browse the term
Definition:	reduced number of thymocytes that have the cell surface marker phenotype CD4-negative, CD8-negative, CD44-negative, and CD25-positive and expressing the T cell receptor beta-chain in complex with the pre-T cell receptor alpha chain.
Synonyms:	exact_synonym:	decreased DN3 alpha-beta immature T lymphocyte number; decreased DN3 alpha-beta immature T-cell number; decreased DN3 cell number; decreased DN3 immature T cell number; decreased TN3 cell number; decreased TN3 thymocyte number; reduced DN3 alpha-beta immature T lymphocyte number; reduced DN3 alpha-beta immature T-cell number; reduced DN3 cell number; reduced DN3 immature T cell number; reduced DN3 thymocyte number; reduced TN3 cell number; reduced TN3 thymocyte number
	xref:	CL:0000807

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Genes (11)

decreased DN3 thymocyte number

term browser

Symbol

Object Name

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

COMM domain containing 10

NCBI chr18:47,091,886...47,221,062
Ensembl chr18:47,091,883...47,367,351

G

hes family bHLH transcription factor 1

NCBI chr16:29,884,175...29,886,614
Ensembl chr16:29,883,202...29,886,614

G

IKAROS family zinc finger 1

NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926

G

leucine rich repeat containing 8A VRAC subunit A

NCBI chr 2:30,127,781...30,153,802
Ensembl chr 2:30,127,727...30,153,802

G

musashi RNA-binding protein 2

NCBI chr11:88,230,208...88,609,197
Ensembl chr11:88,230,208...88,609,339

G

NOC2 like nucleolar associated transcriptional repressor

NCBI chr 4:156,319,112...156,332,073
Ensembl chr 4:156,320,376...156,332,073

G

RPTOR independent companion of MTOR, complex 2

NCBI chr15:6,737,827...6,829,882
Ensembl chr15:6,737,860...6,829,882

G

TSC22 domain family, member 3

NCBI chr X:139,440,277...139,501,271
Ensembl chr X:139,440,277...139,501,408

G

zinc finger and BTB domain containing 1

NCBI chr12:76,416,825...76,443,729
Ensembl chr12:76,417,040...76,443,724

G

zinc finger and BTB domain containing 17

NCBI chr 4:141,171,984...141,195,248
Ensembl chr 4:141,171,965...141,195,241

G

zinc finger protein 131

NCBI chr13:120,226,722...120,253,070
Ensembl chr13:120,226,723...120,252,425

Term paths to the root

Path 1
Term	Annotations
mammalian phenotype	16233
hematopoietic system phenotype	5190
abnormal hematopoietic system morphology/development	4732
abnormal thymus morphology	778
decreased thymocyte number	200
decreased DN3 thymocyte number	11
Path 2
Term	Annotations
mammalian phenotype	16233
hematopoietic system phenotype	5190
abnormal hematopoietic system morphology/development	4732
abnormal hematopoietic cell morphology	3961
abnormal blood cell morphology	2982
abnormal hemopoiesis	1142
abnormal definitive hematopoiesis	1114
abnormal leukopoiesis	858
abnormal lymphopoiesis	736
abnormal T cell differentiation	483
abnormal double-negative T cell morphology	199
decreased double-negative T cell number	92
decreased DN3 thymocyte number	11

paths to the root