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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased circulating creatine kinase level
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Accession:MP:0010091 term browser browse the term
Definition:a reduction in the concentration in the blood of an enzyme that catalyzes the reversible transfer of creatine to phosphocreatine
Comment:There is ambiguity in the literature regarding the terms creatinine kinase and creatine kinase. Most resources insist that creatine kinase is correct. See PMID:17174558 and PMID:14624200 not to mention Wikipedia. Creatine kinase is an enzyme found in the heart, brain, skeletal muscle, and other tissues. Increased amounts of CK are released into the blood when there is muscle damage. The small amount of CK that is normally in the blood comes primarily from skeletal muscles.
Synonyms:exact_synonym: decreased circulating CK level;   decreased circulating CPK level;   decreased circulating creatine phosphokinase level;   decreased circulating creatinine kinase level;   decreased circulating phospho-creatine kinase level;   reduced circulating CK level;   reduced circulating CPK level;   reduced circulating creatine kinase level;   reduced circulating creatine phosphokinase level;   reduced circulating creatinine kinase level;   reduced circulating phospho-creatine kinase level


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Term Annotations click to browse term
  mammalian phenotype 5372
    homeostasis/metabolism phenotype 1393
      abnormal homeostasis 1299
        abnormal enzyme/coenzyme level 81
          abnormal creatine kinase level 8
            abnormal circulating creatine kinase level 3
              decreased circulating creatine kinase level 0
Path 2
Term Annotations click to browse term
  mammalian phenotype 5372
    homeostasis/metabolism phenotype 1393
      abnormal homeostasis 1299
        abnormal blood homeostasis 743
          abnormal circulating protein level 104
            abnormal circulating enzyme level 60
              abnormal circulating creatine kinase level 3
                decreased circulating creatine kinase level 0
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