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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:increased liver cholesterol level
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Accession:MP:0010027 term browser browse the term
Definition:greater than normal amount in the liver of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues
Synonyms:exact_synonym: increased hepatic cholesterol level


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increased liver cholesterol level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp7b ATPase copper transporting beta IAGP RGD PMID:17303181 RGD:2292672 NCBI chr16:76,654,725...76,726,092
Ensembl chr16:76,653,660...76,728,801 		JBrowse link
G Atp7bhts ATPase copper transporting beta; hepatitis IAGP RGD PMID:17303181 RGD:2292672
G Ldlr low density lipoprotein receptor IMP RGD PMID:28469073 RGD:12910100 NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:28,546,146...28,570,675 		JBrowse link
G Ldlrem1Sage low density lipoprotein receptor; ZFN induced mutant 1, Sage IMP RGD PMID:28469073 RGD:12910100
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5440
    liver/biliary system phenotype 136
      abnormal hepatobiliary system morphology 130
        abnormal liver morphology 129
          abnormal liver cholesterol level 16
            increased liver cholesterol level 9
Path 2
Term Annotations click to browse term
  mammalian phenotype 5440
    homeostasis/metabolism phenotype 1430
      abnormal homeostasis 1331
        abnormal lipid homeostasis 364
          abnormal lipid level 359
            increased lipid level 227
              increased sterol level 152
                increased cholesterol level 151
                  increased liver cholesterol level 9
paths to the root