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The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories ( For more information about these ontologies, see the MGI Publications Page at

Term:foam cell reticulosis
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Accession:MP:0009841 term browser browse the term
Definition:an increase in cells with a vacuolated appearance due to abnormal deposition and retention of lipoproteins and derived from or related to the group of cells having the ability to take up and sequester inert particles and vital dyes, including macrophages and macrophage precursors, specialized endothelial cells lining the sinusoids of the liver, spleen, and bone marrow, and macrophages of lymphatic tissue and fibroblasts of bone marrow
Synonyms:exact_synonym: increased foam cell number

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foam cell reticulosis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npc1 NPC intracellular cholesterol transporter 1 IAGP MGI PMID:20007718 PMID:21896731 NCBI chr18:12,322,751...12,369,851
Ensembl chr18:12,322,749...12,369,457
JBrowse link
increased macrophage derived foam cell number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg1 ATP binding cassette subfamily G member 1 IAGP MGI PMID:16054053 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962
JBrowse link
G Adgrf5 adhesion G protein-coupled receptor F5 IAGP MGI PMID:23684610 NCBI chr17:43,671,225...43,770,448
Ensembl chr17:43,671,342...43,770,448
JBrowse link
G Apoe apolipoprotein E IAGP MGI PMID:15567863 PMID:15596719 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 IAGP MGI PMID:23681708 PMID:29908121 NCBI chr 8:41,793,683...41,850,681
Ensembl chr 8:41,793,234...41,827,810
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IAGP MGI PMID:15596719 NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055
JBrowse link
G Ldlr low density lipoprotein receptor IEA MGI NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IAGP MGI PMID:15567863 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Mexis macrophage expressed LXRa(NR1H3)-dependent amplifier of Abca1 transcription lncRNA IAGP MGI PMID:29431742 NCBI chr 4:53,261,356...53,270,232
Ensembl chr 4:53,261,356...53,270,232
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 IAGP MGI PMID:6315811 PMID:22048958 PMID:26019327 NCBI chr18:12,322,751...12,369,851
Ensembl chr18:12,322,749...12,369,457
JBrowse link
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 IAGP MGI PMID:12368482 PMID:27335465 NCBI chr 7:44,199,040...44,204,928
Ensembl chr 7:44,199,040...44,203,375
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 IAGP MGI PMID:12368482 PMID:27335465 NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179
JBrowse link
G Pla2g15 phospholipase A2, group XV IAGP MGI PMID:16880524 NCBI chr 8:106,876,986...106,891,350
Ensembl chr 8:106,877,031...106,891,347
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1, acid lysosomal IAGP MGI PMID:7600574 PMID:12594290 NCBI chr 7:105,203,567...105,207,596
Ensembl chr 7:105,203,567...105,207,596
JBrowse link
G Supv3l1 suppressor of var1, 3-like 1 (S. cerevisiae) IAGP MGI PMID:19145458 NCBI chr10:62,265,000...62,287,294
Ensembl chr10:62,264,988...62,285,517
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  mammalian phenotype 16534
    cellular phenotype 5307
      abnormal cell morphology 1917
        abnormal foam cell morphology 21
          foam cell reticulosis 14
            increased macrophage derived foam cell number 14
paths to the root