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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.

Term:increased susceptibility to infection induced morbidity/mortality
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Accession:MP:0009787 term browser browse the term
Definition:increased likelihood that an organism will display the expected moribund state caused by a pathogenic invasion or from components of or toxins produced by pathogens
Synonyms:exact_synonym: decreased resistance to infection induced morbidity/mortality;   increased sensitivity to infection induced morbidity/mortality



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increased susceptibility to viral infection induced morbidity/mortality term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifnar1 interferon alpha and beta receptor subunit 1 IMP RGD PMID:27999109 RGD:12910492 NCBI chr11:30,725,774...30,752,227
Ensembl chr11:30,725,790...30,749,979
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G Ifnar1em1 interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 1 IMP RGD PMID:27999109 RGD:12910492
G Ifnar1em2 interferon alpha and beta receptor subunit 1; CRISPR/Cas9 induced mutant 2 IMP RGD PMID:27999109 RGD:12910492

Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 5400
    mortality/aging 153
      abnormal induced morbidity/mortality 43
        abnormal susceptibility to infection induced morbidity/mortality 10
          increased susceptibility to infection induced morbidity/mortality 8
            increased susceptibility to bacterial infection induced morbidity/mortality 0
            increased susceptibility to parasitic infection induced morbidity/mortality 0
            increased susceptibility to viral infection induced morbidity/mortality + 8
Path 2
Term Annotations click to browse term
  mammalian phenotype 5400
    immune system phenotype 499
      abnormal immune system physiology 381
        abnormal response to antigen 28
          abnormal response to infection 28
            abnormal susceptibility to infection 28
              increased susceptibility to infection 16
                increased susceptibility to infection induced morbidity/mortality 8
                  increased susceptibility to bacterial infection induced morbidity/mortality 0
                  increased susceptibility to parasitic infection induced morbidity/mortality 0
                  increased susceptibility to viral infection induced morbidity/mortality + 8
paths to the root